Actively Recruiting
Prehabilitation for Colorectal Cancer Patients With Low Functional Capacity and Malnutrition
Led by McGill University · Updated on 2025-05-09
60
Participants Needed
1
Research Sites
252 weeks
Total Duration
On this page
Sponsors
M
McGill University
Lead Sponsor
M
McGill University Health Centre/Research Institute of the McGill University Health Centre
Collaborating Sponsor
AI-Summary
What this Trial Is About
Despite multi-modal prehabilitation (nutrition, exercise, and psychosocial interventions), 60% of older elective colorectal cancer surgery patients with poor physical function were unable to reach a minimum preoperative 400m six-minute walking distance (6MWD), a prognostic cut-point. Compared to the patients that attained \>400m 6MWD preoperatively, twice as many of \<400m patients were malnourished. Malnutrition has long been associated with worse functioning (e.g., physical, immune). The investigators hypothesize that for nutritionally deficient patients, the etiology for their poor physical function is malnutrition. Correction of malnutrition alone might thus be sufficient to achieve a 400m 6MWD before surgery and improve patient outcomes.
CONDITIONS
Official Title
Prehabilitation for Colorectal Cancer Patients With Low Functional Capacity and Malnutrition
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients aged 65 years and older
- Patients with cancer scheduled for primary colorectal resection
- Patients with six-minute walking distance below 400 meters at baseline
- Patients with Patient-Generated Subjective-Global Assessment score of 9 or higher indicating malnutrition
You will not qualify if you...
- History of conditions that prevent exercise, including dementia, Parkinson's disease, or previous stroke with weakness
- Presence of metastatic cancer
- Inability to speak English or French without a companion who can translate
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
MUHC Research Ethics Board
Montreal, Quebec, Canada, H4A 3T2
Actively Recruiting
Research Team
C
Chelsia Gillis, RD PhD
CONTACT
N
Natalia Tomborelli Bellafronte, RD PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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