Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT05945121

Prehabilitation Program to Improve Cardiac Reserve in High-Risk Patients Undergoing Hematopoietic Stem Cell Transplantation

Led by University of Michigan Rogel Cancer Center · Updated on 2026-05-04

10

Participants Needed

1

Research Sites

205 weeks

Total Duration

On this page

Sponsors

U

University of Michigan Rogel Cancer Center

Lead Sponsor

N

National Institutes of Health (NIH)

Collaborating Sponsor

AI-Summary

What this Trial Is About

To assess the feasibility and preliminary effectiveness of a Cardio-Oncology Prehabilitation program in patients at high-risk of developing Cardiovascular (CV) events in improving Cardiorespiratory fitness (CRF) and reducing acute CV complications in Hematopoietic stem cell transplant (HSCT) recipients.

CONDITIONS

Official Title

Prehabilitation Program to Improve Cardiac Reserve in High-Risk Patients Undergoing Hematopoietic Stem Cell Transplantation

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adult 18 years or older
  • Referred for Hematopoietic Stem Cell Transplant evaluation
  • Have at least one cardiovascular risk factor such as hypertension, hyperlipidemia, atrial fibrillation, obesity, heart failure, history of coronary artery disease, or diabetes
  • Able to walk without assistance
  • Able to understand and willing to sign informed consent
  • Able to use Polar Flow heart rate application
Not Eligible

You will not qualify if you...

  • Severe anemia (hemoglobin less than 7 gm/dl)
  • Untreated high-risk coronary artery disease (left main, triple vessel disease)
  • Severe aortic stenosis
  • Recent fracture as reported by the patient
  • Significant balance problems
  • Severe pain during basic movements
  • Unable to walk without assistance or exercise
  • New York Heart Association class IV heart failure
  • Adults unable to give consent, pregnant women, and prisoners

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of Michigan Rogel Cancer Center

Ann Arbor, Michigan, United States, 48109

Actively Recruiting

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Research Team

C

Cancer AnswerLine

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

1

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Prehabilitation Program to Improve Cardiac Reserve in High-Risk Patients Undergoing Hematopoietic Stem Cell Transplantation | DecenTrialz