Actively Recruiting

Age: 18Years +
All Genders
NCT02478892

Preliminary Evaluation of Screening for Pancreatic Cancer in Patients With Inherited Genetic Risk

Led by Abramson Cancer Center at Penn Medicine · Updated on 2026-02-05

200

Participants Needed

1

Research Sites

782 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The study is a prospective, observational study evaluating the utility of endoscopic ultrasound or MRI for the identification of preneoplastic and neoplastic pancreatic lesions in patients at high risk for pancreatic cancer, specifically those with BRCA1/2, ATM, or PALB2 mutations.

CONDITIONS

Official Title

Preliminary Evaluation of Screening for Pancreatic Cancer in Patients With Inherited Genetic Risk

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years or older
  • Documented germline pathogenic or likely pathogenic mutation in BRCA1, BRCA2, ATM, or PALB2
  • If no history of pancreatic cancer in a first or second degree relative, age 50 years or older
  • If there is a history of pancreatic cancer in a first or second degree relative, minimum age is 10 years younger than the age of onset of the youngest affected relative
Not Eligible

You will not qualify if you...

  • Pregnancy

AI-Screening

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Trial Site Locations

Total: 1 location

1

Abramson Cancer Center of the University of Pennsylvania

Philadelphia, Pennsylvania, United States, 19004

Actively Recruiting

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Research Team

B

Bryson Katona, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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