Actively Recruiting

Age: 20Years - 99Years
All Genders
Healthy Volunteers
ID05876117

Clonidine and Lorazepam Premedication for Claustrophobic Patients During MRI Scan

Led by Salem Anaesthesia Pain Clinic · Updated on 2025-01-27

50

Participants Needed

1

Research Sites

286 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Claustrophobia is an intense fear of being confined or suffocated and affects about 5% of people. This fear can make MRI scans difficult because the procedure requires lying still in a narrow tube, which can trigger claustrophobic reactions. Researchers are studying how different premedication options may help reduce claustrophobia symptoms in adults undergoing MRI scans as part of chronic pain management. The study observes adults diagnosed with claustrophobia who have previously been unable to complete an MRI due to their fear. Each participant receives different premedication treatments in rotation before alternate MRI sessions: Lorazepam 1mg, Clonidine 0.2mg, or a combination of both. These medications are given to see if they can reduce claustrophobia during the MRI. Participants will complete the Claustrophobia Questionnaire (CLQ) and the General Anxiety Disorder Questionnaire (GAD-7) on the days before and after each MRI scan to report their symptoms. Researchers will track how many patients complete the MRI scans and analyze changes in anxiety and claustrophobia scores. The study uses statistical methods to evaluate the effects of the premedications on anxiety and scan completion rates.

CONDITIONS

Official Title

Premedication for Claustrophobic Patients for MRI Scan

Who Can Participate

Age: 20Years - 99Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosed with claustrophobia
  • Previous incomplete MRI due to claustrophobia
  • Adult patients
  • Good treatment compliance
  • Reliable Claustrophobia Questionnaire (CLQ) diary
  • Reliable General Anxiety Disorder Questionnaire (GAD) diary
  • Provided informed consent for diary review
  • Provided consent for clinical record quality assurance review
Not Eligible

You will not qualify if you...

  • Poor treatment compliance
  • Cognitive disorder
  • Unable to provide consent
  • Major neuropsychiatric disorder
  • Unreliable diary
  • Cannabis use
  • Excessive alcohol intake
  • Previous adverse or allergic reactions to clonidine
  • Previous adverse or allergic reactions to lorazepam

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Salem Anaesthesia Pain Clinic

Surrey, British Columbia, Canada, V3S 7J1

Actively Recruiting

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Research Team

O

Olu Bamgbade, MD,FRCPC

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

Frequently Asked Questions

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Clonidine and Lorazepam Premedication for Claustrophobic Patients During MRI Scan | DecenTrialz