Actively Recruiting

Age: 20Years - 99Years
All Genders
Healthy Volunteers
NCT05876117

Premedication for Claustrophobic Patients for MRI Scan

Led by Salem Anaesthesia Pain Clinic · Updated on 2025-01-27

50

Participants Needed

1

Research Sites

286 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Claustrophobia is an irrational fear of restriction and suffocation. It is a specific phobia, according to DSM 5. Claustrophobic patients may fear that restriction of their limbs will hinder their ability to move quickly towards safety. MRI may trigger claustrophobia, because this diagnostic procedure involves a patient laying in a narrow tube. Premedication before MRI scan may occasionally reduce claustrophobia. Prospective observational crossover study of claustrophobic patients who are undergoing MRI scan. At alternate MRI scan sessions, each patient receives rotational premedication using Lorazepam 1mg; or Clonidine tablet 0.2mg; or combined Clonidine 0.2mg + Lorazepam 1mg. Patient will use Claustrophobia Questionnaire, a validated tool, to collect data on the days before and after each MRI scan. CLQ is a patient-administered tool used to assess claustrophobia. In addition, patient will use General Anxiety Disorder Questionnaire, a validated tool, to collect data on the days before and after each MRI scan. GAD-7 is a patient-administered tool that is used to assess anxiety.

CONDITIONS

Official Title

Premedication for Claustrophobic Patients for MRI Scan

Who Can Participate

Age: 20Years - 99Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosed with claustrophobia
  • Previous incomplete MRI due to claustrophobia
  • Adult patients
  • Good treatment compliance
  • Reliable Claustrophobia Questionnaire (CLQ) diary
  • Reliable General Anxiety Disorder Questionnaire (GAD) diary
  • Provided informed consent for diary review
  • Provided consent for clinical record quality assurance review
Not Eligible

You will not qualify if you...

  • Poor treatment compliance
  • Cognitive disorder
  • Unable to provide consent
  • Major neuropsychiatric disorder
  • Unreliable diary
  • Cannabis use
  • Excessive alcohol intake
  • Previous adverse or allergic reactions to clonidine
  • Previous adverse or allergic reactions to lorazepam

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Salem Anaesthesia Pain Clinic

Surrey, British Columbia, Canada, V3S 7J1

Actively Recruiting

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Research Team

O

Olu Bamgbade, MD,FRCPC

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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Premedication for Claustrophobic Patients for MRI Scan | DecenTrialz