Actively Recruiting

Phase 3
Age: 20Years - 50Years
All Genders
Healthy Volunteers
NCT06671743

Premedication on Post-endodontic Pain

Led by Gulf Medical University · Updated on 2024-11-04

48

Participants Needed

1

Research Sites

113 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this clinical trial is to compare the efficacy of preoperative administration of alpha-chemo-trypsin, ibuprofen, and acetaminophen in managing post-endodontic pain in patients with symptomatic irreversible pulpitis. The main question it aims to answer is: What is the efficacy of preoperative administration of alpha-chemo-trypsin, ibuprofen, and acetaminophen in managing post-endodontic pain in patients with symptomatic irreversible pulpitis? Participants will undergo root canal treatment after premedication. Researchers will compare \[alpha-chemo-trypsin, ibuprofen, and acetaminophen\] to see the intensity of post-endodontic pain.

CONDITIONS

Official Title

Premedication on Post-endodontic Pain

Who Can Participate

Age: 20Years - 50Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Eligible for root canal treatment
  • Diagnosed with symptomatic irreversible pulpitis with normal apical tissue in mandibular molars
  • Aged between 20 and 50 years
Not Eligible

You will not qualify if you...

  • Taking any medication or analgesics for pain management
  • Having any systemic health issues
  • Allergic to trypsin-chymotrypsin, ibuprofen, or paracetamol
  • Pregnant
  • Having non-restorable teeth
  • Having immature roots
  • Having calcifications
  • Having resorptions

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Gulf Medical University

Ajman, United Arab Emirates, 4184

Actively Recruiting

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Research Team

E

Elsewify

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

QUADRUPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

4

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