Actively Recruiting
Prenatal Analysis of Cell-free Circulating Fetal DNA
Led by University Hospital, Bordeaux · Updated on 2025-09-16
60
Participants Needed
1
Research Sites
50 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
In criminal cases involving sexual assault, victims may later discover they are pregnant, creating profound uncertainty about the paternity of the fetus. These distressing situations compound the trauma already experienced by the victims. To address this, the Medico-Legal Hematology Laboratory (LHML) in Bordeaux aims to validate a method based on Massively Parallel Sequencing (MPS) and a specific isolation protocol for analyzing cell-free circulating fetal DNA (ccfDNA) in maternal blood samples. This identification process will confirm or exclude paternal genetic relationships between the fetus and potential fathers between 6 and 22 weeks of amenorrhea. These analyses will only be conducted under judicial requisition, in accordance with the French Code of Criminal Procedure
CONDITIONS
Official Title
Prenatal Analysis of Cell-free Circulating Fetal DNA
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 or older
- Pregnant woman between 6 and 22 weeks of amenorrhea
- Both mother and father agree to participate and provide signed genetic consent
You will not qualify if you...
- Unknown paternity
- Maternal blood-borne infections such as HIV, syphilis, or hepatitis B
- Father unable to provide a sample
- Insufficient comprehension of French by either parent
- Mother or father under legal protection
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
CHU Bordeaux
Bordeaux, France
Actively Recruiting
Research Team
L
Loic Sentilhes, MD, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
OTHER
Number of Arms
1
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