Actively Recruiting
Preop US-Guided Nerve Blocks for Pain & Recovery After Ankle Arthroscopy
Led by Second Affiliated Hospital, School of Medicine, Zhejiang University · Updated on 2026-03-13
70
Participants Needed
1
Research Sites
47 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This randomized, double-blind controlled trial investigates the effectiveness and potential trade-offs of preoperative ultrasound-guided popliteal sciatic and saphenous nerve blocks in patients undergoing ankle arthroscopy, a procedure often performed in day-case settings but associated with significant early postoperative pain and frequent opioid use. The study evaluates whether these nerve blocks can reduce early postoperative pain-measured by the highest NRS score within 24 hours-and examines their impact on functional recovery, including motor strength and ambulation. All patients receive standardized general anesthesia and multimodal analgesia, with outcomes including opioid consumption, ankle weakness, patient satisfaction, range of motion, muscle strength, hospital stay duration, and analgesia-related costs.
CONDITIONS
Official Title
Preop US-Guided Nerve Blocks for Pain & Recovery After Ankle Arthroscopy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 18 and 65 years
- ASA physical status classification I-II
- Scheduled to undergo ankle arthroscopy under general anesthesia
- Expected to be available for follow-up on the day of surgery (day-case or short-stay surgery)
- Able to understand the procedures and methods of the clinical trial and voluntarily provide written informed consent
- Body mass index (BMI) between 16 and 32 kg/m8
You will not qualify if you...
- History of severe ankle nerve injury or peripheral neuropathy
- Severe cardiac, pulmonary, hepatic, or renal dysfunction
- Chronic pain or regular use of opioid analgesics for more than 3 months
- History of extensive ankle or lower leg surgery that may affect nerve localization
- Psychiatric disorders or cognitive impairment that preclude accurate NRS pain scoring
- Pregnancy or breastfeeding
- Known allergy or contraindication to any of the study drugs
- Any other condition deemed unsuitable for inclusion by the investigators
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
The Second Affiliated Hospital Zhejiang University School of Medicine
Hangzhou, Zhejiang, China
Actively Recruiting
Research Team
Z
zongyou Pan, Doctoral degree
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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