Actively Recruiting
Evaluation of Contrast-enhanced Ultrasonography to Detect Muscle Invasion in Bladder Cancer A Prospective Observational Study
Led by Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University · Updated on 2025-01-13
1000
Participants Needed
1
Research Sites
404 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Bladder cancer includes two main types: non-muscle invasive bladder cancer (NMIBC) and muscle invasive bladder cancer (MIBC). MIBC is more aggressive, harder to treat, and has a higher risk of spreading and poor outcomes. This research aims to evaluate how accurately contrast-enhanced ultrasonography (CEUS) can detect muscle invasion before surgery to help guide better treatment decisions. The study involves using CEUS to examine patients with confirmed primary bladder cancer who have not yet received surgery, chemotherapy, immunotherapy, or other treatments. The goal is to assess the diagnostic performance of CEUS in the preoperative staging of bladder cancer, specifically its ability to detect muscle invasion within a short time frame. Participants will undergo CEUS imaging, and researchers will analyze the results to determine muscle invasion status. The main outcome measured is the detection of muscle invasion within three minutes during imaging. The study includes adults aged 18 to 75 years and monitors safety by excluding those with conditions that could prevent tolerating CEUS or affect accurate diagnosis.
CONDITIONS
Official Title
Preoperative Detection of Muscle Invasion in Bladder Cancer with Contrast-enhanced Ultrasonography
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients aged 18 years or older
- Histologically or cytologically confirmed diagnosis of primary bladder cancer
- No prior surgery, chemotherapy, immunotherapy, or other treatments before CEUS diagnosis
You will not qualify if you...
- No confirmed bladder cancer diagnosis
- Previous pelvic surgery or bladder surgery
- Prior chemotherapy, radiotherapy, or immunotherapy
- Tumor recurrence or metastasis
- Allergy to ultrasound contrast agents or inability to tolerate CEUS due to certain heart or lung conditions such as recent myocardial infarction, angina, cardiac insufficiency, severe arrhythmia, cardiac shunts, severe pulmonary hypertension, uncontrolled hypertension, acute respiratory distress syndrome, or chronic obstructive pulmonary disease
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Sun Yat-sen Memorial Hospital, Sun Yat-sen University
Guangzhou, Guangdong, China, 510120
Actively Recruiting
Research Team
Q
Qiyun Ou, bachelor
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
Similar Trials
Frequently Asked Questions
Have more questions? Get in touch with our team for quick support
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here