Study of Preoperative Ultrasound Elastography to Predict Pancreas Texture and Risk of Complications After Pancreaticoduodenectomy Surgery

What this Trial Is About

Researchers are evaluating the use of preoperative endoscopic ultrasound elastography EUS-E to predict the texture of the pancreas during surgery and the risk of postoperative pancreatic fistula POPF in patients undergoing pancreaticoduodenectomy PD. This study focuses on patients with pancreatic or periampullary diseases, including pancreatic cancer and other related cancers. The aim is to assess whether EUS-E, which measures pancreatic stiffness before surgery, can accurately forecast the pancreass softness or hardness and corresponding surgical outcomes. All participants will receive a preoperative EUS-E exam performed by experienced specialists within one week before their PD surgery. Surgeons will then assess the pancreatic texture during surgery without knowing the EUS-E results to keep evaluations unbiased. The study will follow standard surgical procedures and monitor patients closely for complications such as POPF up to 30 days after surgery. During the study, researchers will collect data from medical records, EUS reports, surgical notes, and pathology reports while maintaining strict confidentiality. They will analyze the accuracy of EUS-E in predicting pancreatic texture and its relationship with POPF severity using statistical methods. Participants will be monitored throughout the surgery and recovery period to evaluate these outcomes, with the total participation lasting from preoperative assessment through at least 30 days post-surgery.

Preoperative EUS Elastography for Pancreatic Texture and POPF Prediction After PD