Actively Recruiting

Phase Not Applicable
Age: 18Years - 65Years
All Genders
NCT07233538

Preoperative Maxillary Nerve Block and Remifentanil Use in Septorhinoplasty

Led by Ankara Etlik City Hospital · Updated on 2025-11-18

90

Participants Needed

1

Research Sites

67 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Septorhinoplasty is generally a prolonged surgical procedure that frequently involves osteotomy, which may lead to increased intraoperative remifentanil requirements. Moreover, it is often associated with significant bleeding due to the dense capillary network of the nasal region, making the maintenance of low-to-normal blood pressure preferable during surgery. Consequently, achieving stable hemodynamics and providing sufficient analgesia throughout the procedure is essential. This study aims to evaluate the effects of bilateral maxillary nerve block on intraoperative remifentanil consumption and postoperative analgesic efficacy in patients undergoing Septorhinoplasty. A total of 90 patients will be included in the study. Forty-five patients (Group M) will undergo Septorhinoplasty under general anesthesia combined with bilateral maxillary nerve block, while the remaining 45 patients (Group N) will receive general anesthesia alone. In the preoperative phase, a bilateral maxillary nerve block will be performed under ultrasound guidance via the pterygopalatine fossa. During the intraoperative period, total remifentanil consumption will be recorded, alongside assessments of hemodynamic stability, sevoflurane consumption, extubation time, intraoperative bleeding volume, and the satisfaction levels of both the anesthesiologist and the surgeon. In the postoperative period, patient satisfaction, pain scores at 0, 1, 2, 4, 6, 12, 18, and 24 hours as well as at 1 month (measured using the Visual Analog Scale - VAS), additional analgesic requirements, and Quality of Recovery-15 (QoR-15) scores (assessed on preoperative day 1, postoperative day 1, and at 1 month) will be evaluated.

CONDITIONS

Official Title

Preoperative Maxillary Nerve Block and Remifentanil Use in Septorhinoplasty

Who Can Participate

Age: 18Years - 65Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • ASA (American Society of Anesthesiologists) score of I or II
  • Body mass index (BMI) between 18 and 30
  • Scheduled for elective surgery
  • Fully cooperative patients who meet criteria for septorhinoplasty surgery
Not Eligible

You will not qualify if you...

  • Conditions contraindicating regional anesthesia such as coagulation disorders, thrombocytopenia, severe valvular heart disease, local infection at injection site, or allergy to local anesthetics
  • International Normalized Ratio (INR) greater than 1.5
  • History or presence of facial paralysis
  • History of central nervous system vascular disease
  • Presence of neuropathy
  • History of surgery in the area where the nerve block will be performed
  • ASA physical status classification of III or higher
  • Unwillingness to participate in the study
  • Chronic pain or chronic opioid use
  • Alcohol, substance, or drug addiction
  • Limited cooperation due to dementia or psychiatric disorders
  • Pregnant or breastfeeding
  • Inability to communicate in native language

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Trial Site Locations

Total: 1 location

1

Ankara Etlik City Hospital

Ankara, Yenimahalle, Turkey (Türkiye)

Actively Recruiting

Loading map...

Research Team

C

Can ozan Yazar, MD

CONTACT

E

Emine ARIK, Associate Professor

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

2

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here

Preoperative Maxillary Nerve Block and Remifentanil Use in Septorhinoplasty | DecenTrialz