Actively Recruiting

Phase 2
Age: 18Years +
MALE
NCT06560905

Preoperative Planning With PSMA-PET in Melanoma Surgery Trial

Led by Royal Marsden NHS Foundation Trust · Updated on 2025-07-01

16

Participants Needed

1

Research Sites

42 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This is a non-randomised, single-centre Phase 2 study, investigating whether the diagnostic biomarker, prostate-specific membrane antigen (PSMA), can detect melanoma metastases using PSMA PET/ CT.

CONDITIONS

Official Title

Preoperative Planning With PSMA-PET in Melanoma Surgery Trial

Who Can Participate

Age: 18Years +
MALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Male aged 18 years or older
  • Biopsy confirmed first or recurrent metastatic melanoma with palpable nodal disease
  • Have undergone staging FDG PET-CT scan as part of routine care
  • Scheduled for surgery to remove the primary melanoma site
Not Eligible

You will not qualify if you...

  • Unable to provide voluntary written informed consent
  • Unwilling to complete all study assessments
  • Female patients
  • Receiving androgen deprivation therapy or androgen receptor antagonist treatments
  • Current or prior diagnosis of prostate cancer
  • Received Lu-177 PSMA therapy or barium studies within 10 days before PSMA PET-CT scan
  • Not fluent in English

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

The Royal Marsden NHS Foundation Trust

London, United Kingdom, SW3 6JJ

Actively Recruiting

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Research Team

R

Reyhaneh Sadegh Zadeh

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

DIAGNOSTIC

Number of Arms

1

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Preoperative Planning With PSMA-PET in Melanoma Surgery Trial | DecenTrialz