Actively Recruiting
Preoperative Radiotherapy and Systemic Therapy Following Surgery in 'de Novo' Metastatic Breast Cancer
Led by Ankara Oncology Research and Training Hospital · Updated on 2022-04-26
40
Participants Needed
1
Research Sites
317 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Locoregional (LRT) of the primary tumor in de-novo metastatic breast cancer (dnMBC) is no longer only a surgical challenge, but more the final decision of a multidisciplinary tumor board including medical oncologists, radiation oncologists and surgical oncologists. It is no longer only a question of locoregional control but rather a wider issue of improving overall survival (OS), due to the possible biological link between primary tumor and metastases. A multimodal approach, including LRT with curative intent should be considered for selected dnMBC patients, especially for the subset of bone-only metastatic ones.
CONDITIONS
Official Title
Preoperative Radiotherapy and Systemic Therapy Following Surgery in 'de Novo' Metastatic Breast Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Primary breast tumor amenable for complete surgical resection
- Patients must be in good physical condition to receive locoregional and systemic treatments including radiotherapy
You will not qualify if you...
- Primary tumor not suitable for complete removal
- Primary tumor with active infection, bleeding, or necrosis
- Poor physical condition preventing protocol treatments
- Synchronous primary cancer in the opposite breast
- Clinically involved lymph nodes on the opposite side
- Unsuitable for adequate follow-up
- Unable to provide informed consent
- Pregnancy or lactation
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Lutfi Dogan
Ankara, Turkey (Türkiye)
Actively Recruiting
Research Team
L
Lutfi Dogan, Prof
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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