Actively Recruiting

Phase Not Applicable
Age: 6Years - 12Years
All Genders
NCT06879431

Preoperative Sleep Intervention on Postoperative Delirium in School-aged Children Undergoing Congenital Heart Surgery

Led by Yan Fuxia · Updated on 2025-05-31

544

Participants Needed

1

Research Sites

87 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This is a multicenter, randomized, controlled clinical trial aimed to determine whether preoperative sleep interventions could reduce the incidence of adverse outcomes, such as postoperative delirium, in sleep-disordered school-aged children undergoing congenital heart surgery. The study will include infants and toddlers undergoing elective cardiac surgery with sleep disorders, assessed by the Children's Sleep Habits Questionnaire (CSHQ). All participants will be randomly assigned to the intervention group and Controll group in a 1:1 ratio. The intervention group received a short intensive cognitive-behavioral intervention 7-14 days before surgery, and no intervention was imposed on the control group. The results of this study will provide suggestions for the prevention of delirium after cardiac surgery.

CONDITIONS

Official Title

Preoperative Sleep Intervention on Postoperative Delirium in School-aged Children Undergoing Congenital Heart Surgery

Who Can Participate

Age: 6Years - 12Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 0 to 36 months
  • Scheduled for elective corrective surgery for congenital heart disease using cardiopulmonary bypass
  • Diagnosed with sleep disorder by Children's Sleep Habits Questionnaire with score greater than 48
Not Eligible

You will not qualify if you...

  • Use of sleep therapy medications before surgery
  • Risk Adjustment in Congenital Heart Surgery-1 (RACHS-1) score 4 or higher
  • History of preoperative cardiac assist device, mechanical ventilation, or asphyxia rescue
  • Emergency surgery or preoperative ICU admission
  • History of neurodevelopmental or psychiatric disorders such as autism, ADHD, or depression
  • Severe liver or kidney dysfunction
  • Presence of non-cardiac malformations like adenoid hypertrophy, tracheobronchial stenosis, polysplenism, anaplastic syndrome, Down syndrome, DiGeorge syndrome, diabetes mellitus, reproductive abnormalities, anal atresia, Williams syndrome, or eye disorders
  • History of preoperative brain ischemia or hypoxia
  • Participation in other clinical trials
  • Family refusal to sign consent or poor compliance by the child

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Fuwai Hospital, Chinese Academy of Medical Sciences

Beijing, China, 100037

Actively Recruiting

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Research Team

F

Fuxia Yan

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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