Actively Recruiting

Age: 18Years +
All Genders
NCT07281040

Preparatory Work for a Trial of Adjuncts to Diuretic Treatment in Patients Hospitalised With Heart Failure: Addressing Uncertainties and Building Consensus

Led by Hull University Teaching Hospitals NHS Trust · Updated on 2025-12-15

10

Participants Needed

1

Research Sites

65 weeks

Total Duration

On this page

Sponsors

H

Hull University Teaching Hospitals NHS Trust

Lead Sponsor

H

Hull York Medical School

Collaborating Sponsor

AI-Summary

What this Trial Is About

Aims and Objectives 1. Choose which adjunctive therapies, at what dose, and for how long 2. Choose the dose(s) of IV furosemide to be used as the comparator 3. Choose primary and secondary outcomes 4. Estimate recruitment and engage sites for a future trial Work package 2a methods overview 1. An online survey of clinicians (doctors, nurses and pharmacists) assessing potential ability to recruit and the acceptability of each adjunct and willingness to support a trial. 2. Evidence generated (survey and reviews) will be considered by an expert panel (N=20-25) including expert clinicians and allied health professionals who care for people with HF using a modified Delphi approach. The panel will make recommendations on all aspects of the trial design. 3. A patient and carer panel of people with a recent hospitalisation (\<6 months) for HF will provide recommendations on trial endpoints. The patient-and-carer advisory group (PCAG) will also input into these discussions.

CONDITIONS

Official Title

Preparatory Work for a Trial of Adjuncts to Diuretic Treatment in Patients Hospitalised With Heart Failure: Addressing Uncertainties and Building Consensus

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Recent hospitalisation with heart failure (less than 6 months) or carer for a person with a recent hospitalisation with heart failure
  • Able to participate in online group discussions in English
Not Eligible

You will not qualify if you...

  • Unable to participate in online group discussions in English

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Cardiology

Hull, Yorkshire, United Kingdom, HU16 5JQ

Actively Recruiting

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Research Team

J

Joe Cuthbert, MBBS MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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