Actively Recruiting

Phase 2
Age: 18Years +
FEMALE
Healthy Volunteers
NCT05953766

Presacral Nerve Block Versus Sham Block on Post-operative Pain for Total Laparoscopic Hysterectomy

Led by Mount Sinai Hospital, Canada · Updated on 2026-04-06

60

Participants Needed

1

Research Sites

40 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The study is a single-center parallel group randomized controlled trial comparing the administration of a presacral nerve block using 20mL of local ropivacaine 5.0mg/ml versus 20mL of normal saline (sham block) on post-operative pain following total laparoscopic hysterectomy.

CONDITIONS

Official Title

Presacral Nerve Block Versus Sham Block on Post-operative Pain for Total Laparoscopic Hysterectomy

Who Can Participate

Age: 18Years +
FEMALE
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • 18 years of age or older
  • Undergoing total laparoscopic hysterectomy
Not Eligible

You will not qualify if you...

  • Previous presacral neurectomy
  • Concurrent surgical procedure other than salpingectomy and/or oophorectomy
  • Gynecological cancer beyond stage 1 disease
  • BMI > 50
  • Chronic opioid consumption
  • Fibromyalgia
  • Language barrier
  • Inability to communicate and provide consent

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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2
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Trial Site Locations

Total: 1 location

1

Mount Sinai Hospital

Toronto, Ontario, Canada, M5G 1X5

Actively Recruiting

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Research Team

M

Mara Sobel, MD

CONTACT

S

Shakiba Ardestani, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

QUADRUPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

2

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Presacral Nerve Block Versus Sham Block on Post-operative Pain for Total Laparoscopic Hysterectomy | DecenTrialz