Fever and antipyretic use in children.
Section on Clinical Pharmacology and Therapeutics, Committee on Drugs, Janice E Sullivan...
https://pubmed.ncbi.nlm.nih.gov/21357332Actively Recruiting
Led by University of Texas at Austin · Updated on 2025-07-20
440
Participants Needed
1
Research Sites
10 weeks
Total Duration
Researchers are evaluating whether providing parents with a prescription for the correct weight-based doses of acetaminophen and ibuprofen reduces unscheduled return visits to the emergency department (ED) within one week for children evaluated for fever. This study focuses on children aged 6 to less than 36 months who are discharged from a pediatric ED. The goal is to understand if prescribing these common fever medicines affects return visits, patient satisfaction, and overall healthcare use. The study is a single-center, randomized controlled trial at a pediatric ED. Participants will be randomly assigned either to an intervention group that receives prescriptions for acetaminophen and ibuprofen with weight-based dosing or to a control group that receives standard printed discharge instructions including dosing information but no prescription. Both groups get the usual discharge education. The study involves 220 children in each group. After discharge, research staff will follow up by phone one week later to check if families made any unscheduled visits to the ED, urgent care, or clinics for similar complaints. They will also assess parental satisfaction with the care received. The main measure is whether an unscheduled return visit occurred within seven days. Secondary measures include total return visits, hospital admissions, and satisfaction levels. Caregivers will be informed about group assignment and asked for permission to continue using collected data for research.
CONDITIONS
Prescription Antipyretics to Decrease Unscheduled Return Visits In A Pediatric Emergency Department
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Complete this quick 3-step screening to check your eligibility
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person) during the emergency department visit
Duration - Discharge day only
Participants are randomized to receive either a prescription with weight-based dosing for acetaminophen and ibuprofen or standardized printed discharge instructions without a prescription.
1 visit (in-person) at discharge from the emergency department
Duration - 7 days after discharge
Approximately one week after discharge, research personnel will contact participants to assess unscheduled return visits and parental satisfaction with emergency department care.
1 follow-up phone call
Total: 1 location
1
Dell Children's Medical Center
Austin, Texas, United States, 78723
Actively Recruiting
L
Lina Palomares, RN, LMSW
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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Section on Clinical Pharmacology and Therapeutics, Committee on Drugs, Janice E Sullivan...
https://pubmed.ncbi.nlm.nih.gov/21357332Sandra Trapani, Adele Fiordelisi, Mariangela Stinco...
https://pubmed.ncbi.nlm.nih.gov/38255334