Actively Recruiting

Age: 18Years +
All Genders
ID06422871

PReSeRVE-HD: Observational Study of the Merit HeRO Graft and Super HeRO Devices in Adults with End-Stage Renal Disease on Hemodialysis

Led by Merit Medical Systems, Inc. · Updated on 2026-06-01

100

Participants Needed

7

Research Sites

78 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are studying adults with end-stage renal disease who require hemodialysis and have experienced failure of other dialysis access options. The study focuses on understanding how safe and effective the Merit Medical HeRO Graft System and Super HeRO Adaptor and Support Seal System devices are for maintaining long-term dialysis access when other options have failed. This observational study is sponsored by Merit Medical Systems, Inc.

CONDITIONS

Brief Title

PReSeRVE-HD: Observational Study of the Merit HeRO® Graft and Super HeRO® in Patients on Hemodialysis

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Subject provides written informed consent
  • Subject is 18 years or older
  • Subject has end-stage renal disease and is on hemodialysis
  • Subject is treated with the HeRO Graft or Super HeRO System according to device instructions for use
Not Eligible

You will not qualify if you...

  • Subject has a previously placed HeRO or Super HeRO device that is being revised or replaced
  • Subject has a topical or subcutaneous infection at the device implantation site
  • Subject has known or suspected systemic infection, bacteremia, or septicemia

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Implementation

Duration - Up to 24 months

Participants undergo treatment attempted with the HeRO® Graft or Super HeRO® device.

Visits at 6, 12, and 24 months for assessments

Long-term Monitoring

Duration - Up to 24 months

Participants are observed for device-related safety events and clinical success after device implementation.

Follow-up visits at 6, 12, and 24 months

Trial Site Locations

Total: 7 locations

1

MedStar Washington Hospital Center

Washington D.C., District of Columbia, United States, 20010

Actively Recruiting

2

Sarasota Memorial Health Care System

Sarasota, Florida, United States, 34239

Actively Recruiting

3

WakeMed

Raleigh, North Carolina, United States, 27610

Actively Recruiting

4

University Pittsburgh Medical Center

Pittsburgh, Pennsylvania, United States, 15219

Actively Recruiting

5

Baylor Scott & White Heart and Vascular Hospital - Dallas

Dallas, Texas, United States, 75226

Actively Recruiting

6

Houston Methodist Hospital

Houston, Texas, United States, 77030

Actively Recruiting

7

Sentara Norfolk General Hospital

Norfolk, Virginia, United States, 23507

Actively Recruiting

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Research Team

H

Hannah Susmeyer

V

Vicky Brunk, RN

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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Frequently Asked Questions

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