Actively Recruiting
The preSPG4 Study - Studying the Prodromal and Early Phase of SPG4
Led by University Hospital Tuebingen · Updated on 2022-08-23
200
Participants Needed
1
Research Sites
700 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Study goals 1. Prospective longitudinal data on progression in the natural course of SPG4 in presymptomatic mutation carriers prior to clinical disease onset and in early stages of disease 2. Biomarkers providing objective measures of disease activity
CONDITIONS
Official Title
The preSPG4 Study - Studying the Prodromal and Early Phase of SPG4
Who Can Participate
Eligibility Criteria
You may qualify if you...
- First degree relatives (parents, offspring, and sibs) of SPG4 patients or symptomatic individuals with known SPAST mutation
- Age 18 to 70 years
- Written, informed consent (patient)
You will not qualify if you...
- No known SPAST-mutation within the family
- Manifest spastic gait (subclinical signs like increased deep tendon reflexes, positive Babinski sign are allowed)
- Participation in interventional trials
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University Hospital Tübingen, Center for Neurology
Tübingen, Germany, 72076
Actively Recruiting
Research Team
L
Ludger Schöls, Prof.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
DIAGNOSTIC
Number of Arms
3
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