Actively Recruiting
Pressure (Fractional Flow Reserve) and Flow (Vascular Flow Reserve) Measurements During Peripheral Arterial Interventions
Led by Dr. Konstantinos Katsanos · Updated on 2025-07-04
100
Participants Needed
1
Research Sites
208 weeks
Total Duration
On this page
Sponsors
D
Dr. Konstantinos Katsanos
Lead Sponsor
M
Medlytic Labs
Collaborating Sponsor
AI-Summary
What this Trial Is About
Fractional Flow Reserve (FFR) and Coronary Flow Reserve (CFR) have been originally developed for physiological assessment of coronary artery disease and may hold potential in the management of Peripheral Arterial Disease (PAD) as well. By adapting pressure and flow measurements for the peripheral arteries, clinicians could objectively evaluate stenosis severity, guiding treatment decisions and optimizing outcomes. The aim of this study is to evaluate the diagnostic performance of FFR and vascular Flow Reserve (VFR, aka CFR) for detection of functionally significant peripheral arterial disease and to derive appropriate cut-off values for the prediction of successful immediate and long-term clinical outcomes.
CONDITIONS
Official Title
Pressure (Fractional Flow Reserve) and Flow (Vascular Flow Reserve) Measurements During Peripheral Arterial Interventions
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Symptomatic peripheral arterial disease including intermittent claudication or critical limb ischemia
- Documented steno-occlusive disease of the femoropopliteal segment by imaging
- Provision of informed consent form
You will not qualify if you...
- Aortoiliac occlusive disease
- Acute limb ischemia
- Aneurysmal infrainguinal disease
- General contraindications to percutaneous balloon angioplasty or other endovascular procedures such as dementia or bleeding disorders
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University Hospital of Patras
Pátrai, Greece
Actively Recruiting
Research Team
K
Konstantinos Katsanos, MSc, MD, PhD, EBIR
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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