Actively Recruiting
Pressure Pain Tolerance in Relation to Balance and Strength in Children
Led by Adly A Adam · Updated on 2025-04-01
80
Participants Needed
1
Research Sites
82 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Sickle cell disease (SCD) is the most frequent life-threatening genetic hemoglobinopathy in the world and occurs due to the synthesis of abnormal hemoglobin S (HbS).Cells with sickle cell hemoglobin are stiff and sticky. When they lose their oxygen, they form into the shape of a sickle or crescent. This can cause pain and tissue damage. Significant decrease in exercise capacity was seen in sickle cell anemic children. In the absence of a guidelines that can guide the prescription of exercise in SCD children. This study is a step for determine the forms of prescription of pain on the balance and muscle strength to build up in future studies a safety of physical exercises for children with sickle cell anemia and improve their functional abilities.
CONDITIONS
Official Title
Pressure Pain Tolerance in Relation to Balance and Strength in Children
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age range was 9-14 years old.
- Ability to follow given instructions.
- Children with sickle cell anemia must be medically stable and take their medications regularly.
- Children with sickle cell anemia must have experienced chronic pain lasting more than 6 months.
- Children with sickle cell anemia must have average weight, height, and body mass index based on age percentiles.
- Healthy children must not participate in regular sports activities, especially those involving lower limb strengthening.
You will not qualify if you...
- Presence of defined cardiovascular or respiratory disorders.
- Renal failure.
- History of myocardial infarction, especially within the last month.
- Unstable angina.
- Recent thoracoabdominal surgery.
- Thoracic or abdominal aneurysm or current pneumothorax.
- Painful vaso-occlusive crises.
- Muscular contractures, joint stiffness, or deformities.
- Neuromuscular problems such as myositis or peripheral neuropathy.
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
El-Tahrir st.- in front of Ben El-Sarayat, Ad Doqi Al Giza, Giza Governate
Giza, Egypt, 002
Actively Recruiting
Research Team
M
Mahmoud M Metwaly, MD
CONTACT
N
Nanees E Salem, PHD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
OTHER
Number of Arms
2
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