Actively Recruiting

Age: 18Years +
All Genders
NCT07252076

PRetreatment MRI for OCcult Liver Metastasis Assessment In Pancreatic Ductal adenocarcinoMa

Led by Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di Alessandria · Updated on 2025-11-26

120

Participants Needed

1

Research Sites

78 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Pancreatic cancer has a low survival rate largely due to late diagnosis and undetected liver metastases. Computed tomography (CT), the standard diagnostic tool, often misses occult metastases that are later discovered during surgery. Recent studies suggest that magnetic resonance imaging (MRI), especially with diffusion-weighted imaging (DWI), can better detect very small liver metastases and help avoid unnecessary surgery. However, MRI is not yet widely used in routine practice due to limited evidence and its selective application. This study proposes incorporating contrast-enhanced MRI and DWI into the diagnostic workflow to improve diagnostic accuracy and guide more effective treatment decisions for patients with pancreatic cancer.

CONDITIONS

Official Title

PRetreatment MRI for OCcult Liver Metastasis Assessment In Pancreatic Ductal adenocarcinoMa

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Male or female patients over 18 years of age
  • New cytological or histological diagnosis of pancreatic ductal adenocarcinoma
  • CT scan showing pancreatic disease meeting minimum imaging criteria
  • MRI performed within 3 weeks after CT scan meeting minimum radiological criteria
  • No prior treatment for pancreatic disease
  • Ability to understand study information and provide written informed consent signed by patient and investigator
Not Eligible

You will not qualify if you...

  • Signs of metastatic disease on initial CT scan, including liver, lung, distant lymph nodes, peritoneal carcinomatosis, or other organs

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

SC Chirurgia Generale

Alessandria, Piedmont, Italy, 15121

Actively Recruiting

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Research Team

C

Clinical Trial Center Clinical Trial Center

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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PRetreatment MRI for OCcult Liver Metastasis Assessment In Pancreatic Ductal adenocarcinoMa | DecenTrialz