Actively Recruiting
Prevalence of Intrauterine Adhesions After D&C With or Without Antiadhesion Gel After Abortion in Second Trimester.
Led by Institute for the Care of Mother and Child, Prague, Czech Republic · Updated on 2024-05-13
200
Participants Needed
3
Research Sites
183 weeks
Total Duration
On this page
Sponsors
I
Institute for the Care of Mother and Child, Prague, Czech Republic
Lead Sponsor
B
Bulovka Hospital
Collaborating Sponsor
AI-Summary
What this Trial Is About
Only patients who sign an informed consent will be included. Patients after a miscarriage in the 2nd trimester of pregnancy who need to perform an instrumental revision of the uterine cavity (RCUI, revisio cavi uteri instrumentalis) will be randomized into two groups. In the first group, RCUI will be performed according to current standards. In the second group, an anti-adhesive preparation with hyaluronic acid (Hyalobarrier gel Endo) will be applied to the uterine cavity at the end of the RCUI procedure. Eight to twelve weeks after the operation, the occurrence of adhesions will be evaluated by ultrasound examination and diagnostic hysteroscopy (if adhesions will be detected, they will be disrupted). The study will also include the completion of a questionnaire in terms of the frequency and strength of the menstrual cycle. The presence of adhesions will be assessed according to The American Fertility Society (AFS).
CONDITIONS
Official Title
Prevalence of Intrauterine Adhesions After D&C With or Without Antiadhesion Gel After Abortion in Second Trimester.
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adult women aged 18 to 40 years who wish to become pregnant in the future
- Experienced a miscarriage in the second trimester of pregnancy (over 12 weeks)
- Undergoing instrumental revision of the uterine cavity (RCUI)
- Signed informed consent to participate in the study
You will not qualify if you...
- Younger than 18 years or older than 40 years
- History of previous uterine surgery such as myomectomy, resection of intrauterine septum, or treatment for intrauterine adhesions
- Suspected molar pregnancy
- Signs of pelvic infection
- Declined participation in the study
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 3 locations
1
1.Lf Uk, Vfn
Prague, Czechia, 12000
Actively Recruiting
2
Instiue for Care of Moher and Childe
Prague, Czechia, 14000
Actively Recruiting
3
FN Bulovka
Prague, Czechia, 14800
Actively Recruiting
Research Team
J
Jiri Hanacek, MD, Ph.D.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here