Actively Recruiting
Prevalence of Long-term Dental Effects of Chemotherapy in Childhood Cancer Survivors Diagnosed With Cancer Before the Age of 10
Led by Cliniques universitaires Saint-Luc- Université Catholique de Louvain · Updated on 2024-11-19
142
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are investigating the long-term dental effects of chemotherapy in individuals who were diagnosed with cancer before the age of 10. The study aims to compare the risk of dental caries and dental development defects between childhood cancer survivors and a control group. This research hopes to improve methods for assessing risks and to support new prevention and treatment strategies for healthy oral development in childhood cancer survivors. Participants will undergo a standard dental examination that includes clinical and radiographic assessments with intra-oral and panoramic X-rays. The study will collect medical data and questionnaires to gather comprehensive information. The comparison involves childhood cancer survivors treated with chemotherapy and a control group without such history. Participants aged 12 to 36 years will be involved for approximately two years. The main outcome measured is the experience of dental caries using the Decay Missing Filled Teeth (DMFT) score. Researchers will also assess the prevalence of dental development defects. The study includes ongoing evaluations during this period to monitor dental health and development.
CONDITIONS
Brief Title
Prevalence of Long-term Dental Effects of Chemotherapy in Childhood Cancer Survivors Diagnosed With Cancer Before the Age of 10
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosed with cancer before age 10 (for childhood cancer survivor group)
- Treated with chemotherapy (for childhood cancer survivor group)
- At least 12 years old at time of follow-up appointment for this study
You will not qualify if you...
- Diagnosed and treated for cancer after age 10
- Under 12 years old at time of study recruitment
- Having syndromes or diseases that affect teeth
- Currently pregnant
- Unable or unwilling to undergo dental and radiographic examination
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Approximately 2 years
Participants complete a questionnaire and undergo a standard dental examination including clinical oral examination and intra-oral and panoramic x-rays.
1 visit (in-person) for dental examination and questionnaire
Trial Site Locations
Total: 1 location
1
Cliniques universitaires Saint-Luc
Brussels, Belgium, 1200
Actively Recruiting
Research Team
A
Armand IRAKOZE
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
DIAGNOSTIC
Number of Arms
2
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