Actively Recruiting
Prevalence of Sarcopenic Obesity in COPD
Led by IRCCS San Raffaele Roma · Updated on 2025-02-12
236
Participants Needed
1
Research Sites
56 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this observational study is to the purpose is to apply of ESPEN/EASO criteria for the diagnosis of sarcopenic obesity and calculation of OS prevalence in a sample of COPD patients. In addition, this study want to evaluate the impact of sarcopenic obesity on the respiratory function of COPD patients and the degree of severity of respiratory disease, assessed by spirometric examination; diaphragm thickness and excursion, by ultrasonographic study; performance, assessed by six-minute walk test (6-MWT); quality of life and degree of dyspnea (mMRC, Barthel dyspnea, S. George Respiratory Questionnaire); compliance and outcomes at the end of the respiratory rehabilitation course. Comparison with normal-weight patients with and without sarcopenia will help to better understand the clinical impact of sarcopenic obesity in this category of patients.
CONDITIONS
Official Title
Prevalence of Sarcopenic Obesity in COPD
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients aged > 40 years of either sex
- Body mass index (BMI) above 18.5
- Stable COPD diagnosis according to GOLD 2021 classification
- Signed informed consent after receiving study information
You will not qualify if you...
- Unstable COPD at enrollment
- Body mass index (BMI) below 18.5
- Presence of tracheostomy
- Uncontrolled hypertension (systolic > 160 mmHg or diastolic > 100 mmHg)
- Hypotension (systolic < 100 mmHg)
- Significant comorbidities limiting exercise tolerance
- Current infectious diseases including HIV
- Active or recent malignancy within 5 years
- Severe neurological, rheumatologic, or musculoskeletal diseases
- History of thoracic surgery
- Severe aortic stenosis, uncontrolled arrhythmias, recent cardiac ischemic event
- Cognitive impairments preventing study understanding or compliance
- Failure to sign informed consent
- Any serious medical condition affecting safety or rehabilitation course
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
IRCCS San Raffaele
Roma, Roma, Italy
Actively Recruiting
Research Team
L
Lucia Gatta, PhD
CONTACT
F
Franco Pasqua, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
3
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