Actively Recruiting

Phase Not Applicable
Age: 18Years - 70Years
All Genders
NCT06430970

Prevalence Of Significant Endoscopic and Histopathologic Findings in Patients Presenting With Unexplained Iron Deficiency Anemia

Led by Mansoura University · Updated on 2024-05-28

124

Participants Needed

1

Research Sites

104 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Background In practice, however, not all anaemic patients undergo appropriate diagnostic tests for the detection of iron deficiency anemia (IDA), and a significant portion of patients with IDA do not receive endoscopic evaluations. Accordingly, this study aimed to detect the prevalence of significant endoscopic (upper and lower endoscopy) and pathological findings in patients presenting with unexplained iron deficiency anaemia. Methods One hundred twenty-four patients with confirmed IDA with no obvious cause who visited the Internal Medicine Clinic were randomly selected. Patients with active bleeding, pregnant or lactating females, or those with contraindications to sedation were excluded. Upper and lower endoscopy were held in the endoscopy unit of Specialized Medical Hospital and tissue biopsy from significant endoscopic findings was sent for histopathological examination.

CONDITIONS

Official Title

Prevalence Of Significant Endoscopic and Histopathologic Findings in Patients Presenting With Unexplained Iron Deficiency Anemia

Who Can Participate

Age: 18Years - 70Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Both males and females aged from 18 to 70 years
  • Confirmed iron deficiency anemia with no obvious cause
  • Presence of significant upper gastrointestinal pathology such as Barrett's esophagus, severe esophagitis, esophagogastric varices, peptic or duodenal ulcers, angioectasia, or cancer
  • Presence of significant lower gastrointestinal pathology such as adenomatous polyps larger than 1 cm, angioectasias, rectal ulcer, irritable bowel syndrome, colon polyps, or cancer
Not Eligible

You will not qualify if you...

  • Active bleeding
  • Pregnant or lactating females
  • Contraindications to sedation including uncontrolled diabetes mellitus, uncontrolled thyroid disorders, pregnancy, or respiratory embarrassment

AI-Screening

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Trial Site Locations

Total: 1 location

1

Mansoura University

Al Mansurah, Dakhlia, Egypt, 35516

Actively Recruiting

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Research Team

A

Asmaa Gameel, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

DIAGNOSTIC

Number of Arms

1

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