Actively Recruiting
Prevalence of Tapia's Syndrome in Weaning Unit
Led by Hopital Forcilles · Updated on 2025-09-15
247
Participants Needed
1
Research Sites
208 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Tapia syndrome is a rare and poorly understood pathology. It is defined by a concomitant attack of the recurrent (branch of X) and hypoglossal (XII) nerves of peripheral or central origin. It is characterized by the paralysis of a vocal cord and the ipsilateral half of tongue. This damage is most often unilateral but it can also be bilateral. It results in dysphonia and swallowing disorders. Tapia syndrome is a rare and poorly understood pathology. To date, less than 100 cases have been described in the literature. Previous works are mainly case reports and literature reviews. No prevalence study has been performed to date. Furthermore, disagreements persist regarding the semiology. Indeed, the involvement of the soft palate is not always described.
CONDITIONS
Official Title
Prevalence of Tapia's Syndrome in Weaning Unit
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Hospitalized in weaning unit
- Intubated with orotracheal tube in ICU for more than 48 hours
- Glasgow score of 13 or higher
- At least 18 years old at time of inclusion
- Affiliated with or beneficiary of a social security system
- Provided oral, free, informed, and express consent
You will not qualify if you...
- Known ENT or neurological disorders such as stroke, head trauma, neurodegenerative disease, brain tumor, or ENT cancer
- Known tumors near the recurrent nerve pathway
- Ortner's syndrome (nerve compression from mitral stenosis)
- Left lung cancer with subaortic lesion
- History of cervical lymph node swelling compressing the recurrent nerve
- Presence of cervical or brain abscess
- Patient on mechanical ventilation for 24 hours
- Patient or trusted person refuses participation
- Person under legal protection or safeguard of justice measure
AI-Screening
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Trial Site Locations
Total: 1 location
1
Hôpital Forcilles
Férolles-Attilly, Seine-et-Marne, France, 77150
Actively Recruiting
Research Team
E
Estelle ROBIN, SLT
CONTACT
A
Aymeric LE NEINDRE, Dr
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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