Study of Tapias Syndrome Prevalence and Related Factors in Patients After Prolonged Orotracheal Intubation in ICU Weaning Unit

What this Trial Is About

Tapia syndrome is a rare condition involving damage to the recurrent and hypoglossal nerves, leading to paralysis of one vocal cord and the same-side half of the tongue. It usually causes voice changes and swallowing difficulties, and is often unilateral but can be bilateral. This study aims to determine how common Tapia syndrome is among patients admitted to a weaning unit after prolonged intubation in the ICU, as well as to describe its clinical and paraclinical features and identify associated risk factors. The study is observational and includes patients who stayed in the ICU with orotracheal intubation lasting longer than 48 hours. Participants are grouped based on whether they have Tapia syndrome or not. Diagnosis involves a lingual clinical exam, nasofibroscopy, and ultrasound. The study tracks clinical signs such as tongue and soft palate involvement, voice impairment, and swallowing disorders. Participants will be evaluated through clinical exams and diagnostic tests following initial swallowing assessments within a week. Researchers will monitor symptoms like dysphonia and dysphagia and use imaging tools like nasofibroscopy and ultrasound to assess nerve involvement. The main outcome is the prevalence of Tapia syndrome measured over about two years. The study also looks at factors linked to the syndrome and collects data during the inclusion day and afterward to understand its features and impact.

Prevalence of Tapia's Syndrome in Weaning Unit