Actively Recruiting

Phase Not Applicable
Age: 14Years - 18Years
All Genders
Healthy Volunteers
NCT05921201

Preventing Depression of Chinese American Adolescents by RRE

Led by Northeastern University · Updated on 2026-03-13

110

Participants Needed

1

Research Sites

148 weeks

Total Duration

On this page

Sponsors

N

Northeastern University

Lead Sponsor

F

Florida A&M University

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this clinical trial is to test if a culturally sensitive mobile health application (Relax, Reflect, Empower-RRE) is feasible and effective in promoting psychological wellbeing and reducing depressive symptoms among Chinese American adolescents (CAA). We will conduct a pilot study of a community sample of 110 CAAs, ages 14-18. We will use adaptive randomization to assign 55 participants to the RRE intervention for 5 days/week for 3 months and 55 to the control group who will receive a wellness check-in text message 5 days/week for 3 months. The main aims/research questions are, 1) To evaluate feasibility and acceptability of RRE. Assessments include both subjective (CAAs' perceptions of feasibility and acceptability of RRE through Mobile Application Rating Scale and open-ended questions) and objective (CAAs' frequency and duration of RRE access automatically recorded) measures. Our hypothesis is that participants in the RRE group will find RRE feasible and acceptable. 2) To investigate CAAs' changes in depressive symptoms, coping self-efficacy, and psychological wellbeing. We will compare if these changes differ in the RRE group and control group. Participants in both RRE and control groups will complete measures of outcomes (depression, coping self-efficacy, psychological wellbeing) and influencing factors (acculturative stress, experiences of discrimination, life events) at three time points: baseline, the end of the preventive intervention (the12th week), and one-month after the intervention (the16th week). Our hypothesis is that CAAs in the RRE group will exhibit lower levels of depressive symptoms and higher levels of coping self-efficacy and psychological well-being in Weeks 12 and 16 than the baseline. Additionally, CAAs in the RRE group will exhibit greater improvement than the control group in the outcome measures from baseline to Weeks 12 and 16.

CONDITIONS

Official Title

Preventing Depression of Chinese American Adolescents by RRE

Who Can Participate

Age: 14Years - 18Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Participants must be Chinese American adolescents (ethnic Chinese descent, born or grew up in the U.S.) from the Greater Boston Area
  • Aged 14 to 18 years and currently enrolled in school
  • Able to understand and sign informed consent or assent for minors
  • Have at least a sixth grade reading level to understand and complete study tasks
Not Eligible

You will not qualify if you...

  • Participants who do not have a sixth grade reading level to understand and complete the measures
  • Diagnosis of major depression or other mental disorders needing more extensive treatment than the RRE program can provide
  • Scored 3 or above on Patient Health Questionnaire-2 or Generalized Anxiety Disorder-2 indicating need for more extensive treatment than the RRE program can provide

AI-Screening

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Trial Site Locations

Total: 1 location

1

Northeastern University

Boston, Massachusetts, United States, 02115

Actively Recruiting

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Research Team

C

CHIEH LI, EdD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

2

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