Actively Recruiting

Phase Not Applicable
Age: 20Years - 50Years
All Genders
NCT07303543

Preventing Muscle Loss After Bariatric Surgery: Protein-Collagen Supplementation and Resistance Exercise

Led by Medipol University · Updated on 2025-12-26

35

Participants Needed

1

Research Sites

182 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The aim of this clinical trial is to investigate the effectiveness of collagen, considered a new approach to prevent muscle mass loss after bariatric surgery, and to demonstrate the relationship between this effect and exercise. The key questions it aims to answer are: Does whey protein supplementation with collagen combined with resistance exercise prevent muscle mass loss after bariatric surgery? Do whey protein supplementation with collagen combined with resistance exercise affect fat mass after bariatric surgery? Researchers will compare collagen with whey protein. The study groups and interventions to be implemented are summarized below: Group 1: Control Group (CG; n: 10) Whey protein supplementation will be administered Vitamin and mineral supplementation will be administered No resistance exercise will be performed The participants will eat according to bariatric surgery nutrition guidelines and perform physical activities. Group 2: Whey Protein + Collagen + Exercise Group (WPCEG; n: 10) Whey protein supplements with collagen will be given. Vitamin and mineral supplements will be given. Resistance exercise will be performed. They will eat according to bariatric surgery nutrition guidelines and perform physical activities. They will begin a resistance exercise program 4 weeks after surgery. Group 3: Whey Protein + Collagen + No Exercise Group (WPCG; n: 10) Whey protein supplements with collagen will be given. Vitamin and mineral supplements will be given. No resistance exercise will be performed. They will eat according to bariatric surgery nutrition guidelines and perform physical activities. Group 4: Whey Protein + Exercise Group (WPEG; n: 10) Whey protein supplements will be given. Vitamin and mineral supplements will be given. Resistance exercise will be performed. They will eat according to bariatric surgery nutrition guidelines and perform physical activities. A resistance exercise program will begin at 4 weeks post-operatively.

CONDITIONS

Official Title

Preventing Muscle Loss After Bariatric Surgery: Protein-Collagen Supplementation and Resistance Exercise

Who Can Participate

Age: 20Years - 50Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Be between 20 and 50 years old
  • Have a body mass index (BMI) between 35 and less than 60 kg/m2
  • Not be pregnant
  • Not be addicted to alcohol or drugs
  • Not have entered menopause
  • Have no exercise restrictions
Not Eligible

You will not qualify if you...

  • Have inflammatory bowel diseases, upper gastrointestinal bleeding, advanced psychiatric diseases, cancer, or kidney failure
  • Use statin medications
  • Be pregnant
  • Be addicted to alcohol or drugs
  • Have entered menopause
  • Have exercise restrictions
  • Be a professional athlete
  • Have done more than 60 minutes of regular, structured exercise per week in the last year

AI-Screening

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Trial Site Locations

Total: 1 location

1

Istanbul Medipol University

Istanbul, Fatih, Turkey (Türkiye)

Actively Recruiting

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Research Team

R

Rüken A Samancı, Msc

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

TRIPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

4

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