Comparison of the Safety Planning Intervention With Follow-up vs Usual Care of Suicidal Patients Treated in the Emergency Department.
Barbara Stanley, Gregory K Brown, Lisa A Brenner...
https://pubmed.ncbi.nlm.nih.gov/29998307/Actively Recruiting
Led by Johns Hopkins University · Updated on 2026-07-08
484
Participants Needed
6
Research Sites
4 weeks
Total Duration
This research focuses on suicidal youth aged 12 to 24 in diverse urban areas across the United States. It compares two brief, evidence-based interventions designed to prevent suicidal crises the Stanley Brown Safety Planning Intervention with Follow-up Contacts SPI, and Interpersonal Psychotherapy for Adolescents Ultra Short Crisis Intervention IPT-A SCI. The study aims to determine which intervention is more effective and acceptable for youth at risk of suicide presenting in emergency department settings, informing future standards of care. Participants receive one of two interventions. SPI is delivered in the emergency department and includes creating a personalized safety plan with follow-up contacts after discharge to check mood, review the plan, and connect with community mental health services. IPT-A SCI is a five-session outpatient psychotherapeutic treatment focusing on teaching skills to prevent suicidal crises and addressing interpersonal problems contributing to suicide risk. Both approaches are scalable and target crisis prevention differently. During the study, participants will be assessed at baseline and followed up at 3, 6, and 12 months. Evaluations include measures of suicidal ideation, suicidal behavior, mental health service use, quality of life, anxiety, depression, family and peer relationships, and skill use related to each intervention. The study tracks the number of suicides over 12 months and uses validated tools such as the Columbia-Suicide Severity Rating Scale. Participants will be monitored throughout the 12-month follow-up period to evaluate outcomes and safety.
CONDITIONS
Preventing Suicidal Behavior With Diverse High-Risk Youth in Acute Care Settings
H
Holly C Wilcox, PhD
C
Catherine Grela
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Johns Hopkins University
Lead Sponsor
Johns Hopkins All Children's Hospital
Collaborating Sponsor
This table compares participation in this trial with other options available for this condition. The information is drawn from published research and the trial’s study details and is provided for educational purposes only.
| Factors | SPI+ | IPT‑A‑SCI |
|---|---|---|
| What it is | A brief safety planning intervention delivered in the emergency department followed by three structured follow‑up contacts during the 12‑month period | An ultra‑brief crisis‑focused adaptation of interpersonal psychotherapy for adolescents involving five sessions, delivered during the acute care period |
| Role in trial | One of two randomized behavioral suicide prevention strategies | The other randomized behavioral suicide prevention strategy being evaluated |
| Primary use | Prevent suicidal ideation and behavior during and after acute care | Reduce suicidal ideation and behavior in high‑risk adolescents following acute suicidal crisis |
| How it is given or performed | Safety plan created in emergency department with three outreach follow‑up contacts over 12 months | Five-session ultra‑brief IPT‑A crisis sessions delivered during acute period |
| Evidence status | Effectiveness in adolescents with acute suicidal crisis under evaluation in this randomized trial | Pilot data suggest feasibility and initial promise in reducing suicidal ideation, but efficacy in broader population under study in this trial |
| Important risks | Not yet established; safety under evaluation in trial | Not yet established; safety under investigation in this pilot and main trial |
| Important limitations | Effectiveness beyond acute care and across diverse populations unknown until trial completes | Pilot data based on small samples; larger randomized results awaited |
| Patient impact | null | null |
Disclaimer: This comparison is created with the help of artificial intelligence(AI) and may contain errors or missing information. It is not medical advice and does not mean one option is better or safer than another. Clinical trials are still being studied, and joining a trial is your choice. Please consult your healthcare professional before making any decisions.
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Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - Up to 12 months
Participants receive one of two behavioral interventions to prevent suicidal crises: the Safety Planning Intervention with follow-up contacts or the Interpersonal Psychotherapy for Adolescents Ultra Short Crisis Intervention.
Multiple visits over 12 months including baseline, 3, 6, and 12 month assessments
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
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Barbara Stanley, Gregory K Brown, Lisa A Brenner...
https://pubmed.ncbi.nlm.nih.gov/29998307/Liat Haruvi Catalan, Mira Levis Frenk, Ella Adini Spigelman...
https://pubmed.ncbi.nlm.nih.gov/33362595/Johns Hopkins University
Lead Sponsor
Johns Hopkins All Children's Hospital
Collaborating Sponsor