Wound infection in cardiothoracic surgery.
F C Wells, S W Newsom, C Rowlands
https://pubmed.ncbi.nlm.nih.gov/6134001Actively Recruiting
Phase Not Applicable
Age: 18Years +
All Genders
Healthy Volunteers
ID06603961
Efficacy of Customized Pressure-Guided Elastic Bandages in Preventing Postoperative Edema and Complications in Coronary Artery Bypass Graft Patients
Led by Siriraj Hospital · Updated on 2026-02-09
106
Participants Needed
2
Research Sites
8 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are evaluating the use of customized pressure-guided elastic bandages (CPG-EB) to prevent swelling and complications after coronary artery bypass graft (CABG) surgery. The study focuses on patients undergoing CABG with saphenous vein harvesting and compares the effectiveness of CPG-EB against standard post-surgery care. Compression therapy has shown benefits in reducing swelling, but cost concerns exist. The CPG-EB method aims to improve venous blood flow and reduce postoperative issues. Participants are randomly assigned to one of two groups: the intervention group receives the customized pressure-guided elastic bandage for four weeks after surgery, while the standard group follows usual care, which includes wearing elastic bandages for 24 hours or overnight. The study collects data at 1, 2, and 6 weeks post-surgery to assess swelling and wound complications using standardized criteria. During the study, participants undergo regular evaluations to measure leg swelling incidence, severity, and changes in leg circumference at different locations compared to preoperative measurements. Researchers also monitor infection rates, delayed wound healing, and numbness at the surgical site at the same time points. The study aims to capture comprehensive data on postoperative recovery and complications over six weeks following surgery.
CONDITIONS
Brief Title
Prevention of Edema After Coronary Artery Bypass Graft by Customized Pressure-guided Elastic Bandages
Who Can Participate
Age: 18Years +
All Genders
Healthy Volunteers
Eligibility Criteria
You may qualify if you...
- Scheduled for elective coronary artery bypass grafting (CABG) surgery with saphenous vein harvesting from the leg at Siriraj Hospital
- Aged 18 years or older
- Willing to consent to participate in the study
You will not qualify if you...
- Ankle-brachial pressure index (ABI) less than 0.8
- Severe leg swelling (pitting edema grade 3 or higher) or uncontrolled pre-existing or post-operative heart failure despite diuretic therapy
- Occlusive peripheral arterial disease or chronic venous insufficiency with symptoms such as venous stasis, leg pain, varicose veins, or lymphadenopathy
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
1
2
3
Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Surgery and Immediate Post-operative Care
Duration - 1 day
Participants undergo elective coronary artery bypass graft surgery with saphenous vein harvesting and receive initial post-operative care.
1 visit (in-person)
Treatment
Duration - 4 weeks
Participants in the intervention group receive customized-pressure guided elastic bandages for 4 weeks post-operatively, while the standard group uses elastic bandages for 24 hours or overnight after surgery.
Weekly visits for up to 4 weeks
Post-operative Follow-up
Duration - 6 weeks
Participants are monitored for leg swelling, infection, wound healing, and numbness at 1, 2, and 6 weeks after surgery.
3 visits (in-person) at 1, 2, and 6 weeks post-surgery
Trial Site Locations
Total: 2 locations
1
Faculty of Medicine Siriraj Hospital, Mahidol University
Bangkok, Bangkok Noi, Thailand, 10700
Not Yet Recruiting
2
Siriraj hospital
Bangkok, Bangkok Noi, Thailand, 10700
Actively Recruiting
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Research Team
R
Ratcharnon Srifa, MD
N
Nachasa Khongchu, MSc
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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Published Research Related To This Trial
Preoperative correlates of impaired wound healing after saphenous vein excision.
J R Utley, M E Thomason, D J Wallace...
https://pubmed.ncbi.nlm.nih.gov/2786980Venous function and delayed leg swelling following saphenectomy in coronary artery bypass grafting.
Y Terada, S Fukuda, E Tohda...
https://pubmed.ncbi.nlm.nih.gov/10614096Use of customised pressure-guided elastic bandages to improve efficacy of compression bandaging for venous ulcers.
Nuttawut Sermsathanasawadi, Choedpong Chatjaturapat, Rattana Pianchareonsin...
https://pubmed.ncbi.nlm.nih.gov/27502619Wound complications of the in situ saphenous vein bypass technique.
T Reifsnyder, D Bandyk, G Seabrook...
https://pubmed.ncbi.nlm.nih.gov/1578540Risks and contraindications of medical compression treatment - A critical reappraisal. An international consensus statement.
Eberhard Rabe, Hugo Partsch, Nick Morrison...
https://pubmed.ncbi.nlm.nih.gov/32122269Major leg wound complications after saphenous vein harvest for coronary revascularization.
C E Paletta, D B Huang, A C Fiore...
https://pubmed.ncbi.nlm.nih.gov/10969669Use of support stockings after cardiac surgery.
B O'Hagan, S Kolvekar
https://pubmed.ncbi.nlm.nih.gov/12026465Saphenous neuralgia after coronary artery bypass grafting.
J Mountney, G A Wilkinson
https://pubmed.ncbi.nlm.nih.gov/10571092Compression therapy in mixed ulcers increases venous output and arterial perfusion.
Giovanni Mosti, Maria Letizia Iabichella, Hugo Partsch
https://pubmed.ncbi.nlm.nih.gov/21944912