Actively Recruiting

Phase Not Applicable
Age: 75Years +
All Genders
Healthy Volunteers
NCT06634147

Prevention of Functional and Cognitive Impairment Through a Multicomponent Exercise Program in Hospitalized Older Adults

Led by Fundacion Miguel Servet · Updated on 2025-07-18

296

Participants Needed

2

Research Sites

95 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this clinical trial is to determine whether a multicomponent exercise program improves functional capacity and cognitive status in hospitalized elderly patients aged 75 and older. Additionally, the study aims to assess the impact of this program on medication use, quality of life, and overall health outcomes. Key questions include whether the program enhances functional and cognitive capacities and which subgroups benefit most, such as frail patients or those with cognitive impairment. Participants will engage in a structured exercise program that includes strength training, balance exercises, and walking, all designed to improve mobility and reduce fall risk. They will attend supervised sessions several times a week, allowing for individualized attention and adjustments based on their abilities and health status. Throughout the study, changes in functional capacity will be monitored using standardized assessments that measure mobility, strength, and overall physical functioning. Cognitive assessments will evaluate any changes in cognitive status during the intervention and follow-up periods post-discharge. Participants will provide information on medication usage to analyze whether the exercise program can reduce the need for medications or help manage common polypharmacy issues. Surveys and interviews will assess participants' quality of life, including physical, emotional, and social well-being, before and after the intervention. Follow-up assessments will track progress and outcomes, ensuring long-term benefits of the exercise program are documented. The study will include a diverse sample from multiple centers, focusing on individuals aged over 75 who are hospitalized in Geriatrics and Internal Medicine services across participating centers (HUN, CHU-T, ULSBM, and HNSM). Exclusion criteria will ensure safety, excluding those with terminal illnesses or significant contraindications for exercise. This clinical trial aims to recruit 296 patients, providing valuable insights into the benefits of physical activity for elderly patients during hospitalization and informing future care practices.

CONDITIONS

Official Title

Prevention of Functional and Cognitive Impairment Through a Multicomponent Exercise Program in Hospitalized Older Adults

Who Can Participate

Age: 75Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Age equal to or greater than 75 years, admitted to the acute care unit for medical conditions.
Not Eligible

You will not qualify if you...

  • Explicit refusal to participate or inability to provide informed consent by the patient or legal representative.
  • Life expectancy less than 3 months or terminal oncological or non-oncological disease.
  • Inability to follow up during the study.
  • Inability to participate in a multicomponent exercise program.
  • Medical contraindication to exercise.
  • Moderate to severe major neurocognitive disorder (GDS - Fast Reisberg 5-7).
  • Moderate to severe disability (Barthel Index less than 60).
  • Expected hospital stay less than 6 days.

AI-Screening

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Trial Site Locations

Total: 2 locations

1

Hospital Universitario de Navarra - Navarrabiomed

Pamplona, Navarre, Spain, 31008

Actively Recruiting

2

Hospital Universitario de Navarra

Pamplona, Navarre, Spain, 31008

Actively Recruiting

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Research Team

N

Nicolas Martinez-Velilla, PhD

CONTACT

F

Fabricio Z Zambom-Ferraresi, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

SINGLE_GROUP

Primary Purpose

PREVENTION

Number of Arms

2

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