Prevention of Incisional Hernia After Renal Transplantation Using ProGrip Mesh

What this Trial Is About

Researchers are evaluating the effectiveness of mesh reinforcement in closing the abdominal incision after kidney transplantation to reduce the chance of developing incisional hernias within 2 years after surgery. Incisional hernias are defects or bulges at the surgical scar site that can cause complications and may require further surgery. This study focuses on kidney transplant patients who face higher hernia risks due to immunosuppressive treatments and other factors like obesity and female sex. The trial compares two methods of closing the surgical wound: one group receives a self-gripping polyester mesh called ProGrip placed above the muscle layer to reinforce the closure without additional stitches. The control group has the incision closed using a standard two-layer suture technique with long-lasting absorbable thread. Both groups have a small drain placed under the skin after surgery to remove fluids for a few days. Participants will be followed for 24 months after their transplant, with check-ups at 3, 6, 12, and 24 months. These visits include physical exams, lab tests, monitoring for side effects, and a CT scan at the end of the study to detect hernias. The study aims to measure how well the mesh prevents hernias and to assess the safety of this approach. A total of 160 adult first-time kidney transplant recipients will take part, with obesity being considered in how participants are assigned to groups.

Prevention of Incisional Hernia After Renal Transplantation