Preventing Surgical Site Infection in Children Undergoing Open Groin Surgery Using Intravenous Antibiotics and Antimicrobial Sutures

What this Trial Is About

This clinical trial investigates whether intravenous prophylactic antibiotics and antimicrobial-coated sutures can reduce surgical site infections in children undergoing open groin surgeries. It aims to compare no antibiotic use, intravenous prophylactic antibiotics, and antimicrobial-coated sutures to see which approach may better prevent infections after surgery. Participants will be randomly assigned on the day of surgery to one of three groups one receiving a placebo injection with non-coated sutures, another receiving intravenous prophylactic antibiotics with non-coated sutures, and a third receiving a placebo injection with antimicrobial-coated sutures. The study is double blinded and controlled to ensure unbiased results. During the study, children will have their surgical wounds examined at clinic visits on postoperative days 5, 13, and 30 to check for signs of infection. The main outcome measured is the occurrence of surgical site infection within 30 days after surgery. This monitoring follows CDC guidelines to ensure consistent assessment of wound healing and infection status.

Prevention of Surgical Site Infection in Open Paediatric Groin Surgeries Using Intravenous Prophylactic Antibiotics and Antimicrobial-coated Sutures