Actively Recruiting
Prevention and Treatment of AKI VEXUS Guided Post Cardiac Surgery
Led by Onassis Cardiac Surgery Centre · Updated on 2025-05-14
304
Participants Needed
1
Research Sites
117 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The main goal of this clinical trial is to learn if evaluation by ultrasound of venous congestion of liver and kidneys can guide treatment and prevent and treat acute kidney injury post cardiac surgery (CSA-AKI). Participants will: Be evaluated by liver and kidney veins ultrasound (treatment group) or a placebo post CSA-AKI. Fluid management for the treatment group will be based on a score that emerges from this evaluation (Venous Excess Ultrasound Score, VEXUS). Kidney function will be daily monitored and followed-up for 7 days and until discharge. Daily fluid balance and laboratory examination will be performed. Data will be recorded and collected and a statistical analysis will provide the results that will show or not a probable superiority of this evaluation comparing to the usual care.
CONDITIONS
Official Title
Prevention and Treatment of AKI VEXUS Guided Post Cardiac Surgery
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients in the Cardiac Surgery ICU who develop acute kidney injury according to KDIGO criteria within 48 hours of ICU admission after cardiac surgery
- Elective and non-elective cardiac surgery
You will not qualify if you...
- Patient refusal
- Severe chronic renal failure (GFR <15 mL/min/m2 or on hemodialysis)
- Critical preoperative condition (severe cardiogenic shock, resuscitated cardiac arrest, support with mechanical circulatory assist devices)
- Liver cirrhosis or inferior vena cava obstruction
- Pregnancy
- Morbid obesity (BMI >40 kg/m2)
- Delirium or other condition that prevents the performance of an ultrasound study
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Onassis Cardiac Surgery Center
Athens, Kallithea, Greece, 17674
Actively Recruiting
Research Team
S
Stavros Dimopoulos, PhD, EDIC
CONTACT
K
Konstantina Kolonia, MD, MSc
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
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