Actively Recruiting
Preventive Therapy of Postoperative Intra-abdominal Infection Based on Serum Lactate Changes
Led by Peking Union Medical College Hospital · Updated on 2021-09-27
297
Participants Needed
1
Research Sites
260 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Intra-abdominal infection is one of the most serious complications after pancreatic resection. The preventive use of antibiotics intraoperatively could reduce the incidence rate of postoperative intra-abdominal infection. According to the previous retrospective study, changes of serum lactate level on postoperative day1 could predict the incidence rate of postoperative intra-abdominal infection. This prospective RCT is to further validate and promote the findings and conclusion.
CONDITIONS
Official Title
Preventive Therapy of Postoperative Intra-abdominal Infection Based on Serum Lactate Changes
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Undergoing pancreatic resection such as pancreaticoduodenectomy, pancreatosplenectomy, total pancreatectomy, or related surgeries
- Being cared for in the intensive care unit after surgery with standard serum lactate treatments
- Complete data available from before, during, and after surgery
- Peak serum lactate level greater than 3.250 mmol/L within 24 hours after surgery
You will not qualify if you...
- History of any upper abdominal surgery before current hospital admission
- Minimum mean arterial pressure below 65 mmHg during surgery
- Lack of written informed consent for perioperative care and related studies
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Peking Union Medical College Hospital
Beijing, Beijing Municipality, China, 100730
Actively Recruiting
Research Team
Y
Yatong Li, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
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