Actively Recruiting
Prilocaine for Sphenopalatine Ganglion Block in Endoscopic Hypophysectomy
Led by Kasr El Aini Hospital · Updated on 2025-12-05
54
Participants Needed
1
Research Sites
8 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Patients undergoing endoscopic surgeries for pituitary adenoma excision suffer from wide swings in blood pressure that might increase bleeding and interfere with the surgical field. Local anethetic infiltration and regional nerve blocks have been used to provide better analgesia, control blood pressure and improve surgical field. Limited studies evaluated shenopalatine ganglion block in pituitary adenoma excision with promising outcomes. The proposed study will compare the efficacy of two local anesthetics, prilocaine and lidocaine, for spenopalatine ganglion block in patients undergoing endoscopic pituitary adenoma excision. Evaluating the control of the intraoperative blood pressure and analgesic sparing are the main objectives of the proposed study.
CONDITIONS
Official Title
Prilocaine for Sphenopalatine Ganglion Block in Endoscopic Hypophysectomy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with pituitary adenoma undergoing endoscopic hypophysectomy.
- ASA physical status I and II.
- Age above 21, below 45 years.
- Male or female
You will not qualify if you...
- Age below 21 years or above 45 years.
- Disturbed conscious level.
- Coagulation abnormalities.
- Poorly controlled blood pressure and/or heart rate.
- Increased intracranial tension.
- Liver and kidney disorders.
- Use of anticoagulants and/or NSAIDs.
- Addiction to drugs and/or alcohol.
- Disturbed conscious level at the end of surgery with Glasgow Coma Scale >14.
AI-Screening
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Trial Site Locations
Total: 1 location
1
Kasr El Ainy
Cairo, Egypt, 11956
Actively Recruiting
Research Team
R
Rania Fahmy, Associate Professor
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
3
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