Actively Recruiting

Age: 18Years - 65Years
All Genders
NCT04020783

Primary Aldosteronism: Prospective Screening Registry in China

Led by Shanghai Jiao Tong University School of Medicine · Updated on 2024-08-13

10000

Participants Needed

1

Research Sites

332 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

1. Study name: A prospective study of the incidence and outcomes of Primary aldosteronism in Chinese hypertensive patients 2. Rationale: Unlike essential hypertension, secondary hypertension is caused by certain defined diseases or causes. For this reason, secondary hypertension can often be cured or effectively controlled. As one of the most common types of secondary hypertension, it is estimated that primary aldosteronism (PA) accounts for 5%-10% of all hypertensive patients, accounting for about 20% of patients with refractory hypertension. 3. Objective: 1) Collect and analyze the population and disease characteristics of Chinese PA patients; 2) Strengthen the awareness of screening for PA in people with high blood pressure. 4. Study design: Prospective , multi-center, observational study. 5. Study population: Hypertensive patients with high suspected or confirmed of primary aldosteronism. 6. Treatment: Standardized diagnosis and treatment procedure as recommended in the international guidelines of PA. 7. Follow up: 6, 12 and 24 months after diagnosis. 8. Sample size estimation: About 10 thousand. 9. Timeline: Start of subjects enrollment: July 2019; End of subjects enrollment: December 2022; End of study: December 2024. 10. Organization: The Centre for Epidemiological Studies and Clinical Trials, Ruijin Hospital, Shanghai, China.

CONDITIONS

Official Title

Primary Aldosteronism: Prospective Screening Registry in China

Who Can Participate

Age: 18Years - 65Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 to 65 years old
  • Diagnosed with hypertension
  • Plasma aldosterone renin ratio (ARR) greater than 40
  • Provided informed consent to participate in the study
Not Eligible

You will not qualify if you...

  • Not eligible as determined by the investigator or not meeting inclusion criteria

AI-Screening

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Trial Site Locations

Total: 1 location

1

Shanghai Institite of Hypertension, Ruijin Hospital, Shanghai Jiaotong University School of Medicine

Shanghai, China, 200025

Actively Recruiting

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Research Team

J

Jiguang Wang, MD, PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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Primary Aldosteronism: Prospective Screening Registry in China | DecenTrialz