Actively Recruiting
The Primary Purpose of This Study is to Determine if Biotin, Vitamin B7 is an Effective Way to Label Platelets in Survival and Recovery Studies.
Led by Bloodworks · Updated on 2026-04-30
12
Participants Needed
1
Research Sites
34 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This is a platelet transfusion study. The primary purpose of this study is to determine if Biotin, vitamin B7 is an effective way to label platelets in survival and recovery studies. This study involves using a radioactive material as well as Biotin added to platelets to track platelets in the blood. The platelets will be collected using an apheresis procedure, labeled with biotin, and stored for 3 days. After the storage period, a radioactive material will be added to a small amount of the stored biotin-treated platelets. The radiolabeled platelets will be given back to donor and follow-up blood draws will be done to see how many of the platelets are circulating.
CONDITIONS
Official Title
The Primary Purpose of This Study is to Determine if Biotin, Vitamin B7 is an Effective Way to Label Platelets in Survival and Recovery Studies.
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Normal health status
- Meet Bloodworks Northwest guidelines for autologous apheresis platelet donation
- Screening chemistry and hematology lab results within normal limits
- Negative blood donor screening panel for HIV, Hepatitis B, and Hepatitis C
- Agreeable to birth control measures during the study
You will not qualify if you...
- Presence of clinically significant acute or chronic disease
- Pregnant or lactating females
- Participation in a clinical research study within 30 days before platelet collection
- Treatment with aspirin-containing medications within 7 days before platelet collection
- Treatment with platelet-inhibiting medications within 14 days before platelet collection
- Splenectomized donor
- Presence of anti-biotin or antiplatelet antibody at screening
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Bloodworks Northwest Research Institute
Seattle, Washington, United States, 98102
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
BASIC_SCIENCE
Number of Arms
1
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