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ID04772768

Study of Patients With Prior Coronary Artery Bypass Graft Surgery Having Saphenous Vein Graft Problems and Coronary Artery Disease Progression

Led by Amsterdam UMC, location VUmc · Updated on 2023-06-02

500

Participants Needed

1

Research Sites

260 weeks

Total Duration

AI-Summary

What this Trial Is About

This research aims to study patients who have had coronary artery bypass grafting CABG surgery and have at least one saphenous vein graft SVG, especially those experiencing recurrent ischemic symptoms. The goal is to understand clinical outcomes related to graft failure and progression of native coronary artery disease CAD. This observational study focuses on patients often older with complex heart conditions who are evaluated for these issues, as current treatment guidelines are limited for this group. Participants will be observed without intervention, with data collected from national registries, electronic medical records, and standardized phone assessments at 3 and 5 years after enrollment. Diagnostic results from non-invasive and invasive tests, such as graft patency and heart function assessments, will be gathered to evaluate their usefulness in guiding repeat revascularization treatments. During the study, participants will undergo regular follow-up assessments at 3 and 5 years to monitor major cardiovascular events and graft status. Quality of life will be measured using specific heart-related questionnaires. Researchers will also track procedural success and mortality for patients who undergo further interventions. The total observation period includes ongoing data collection through medical records and patient contact to better understand long-term outcomes after CABG.

CONDITIONS

Brief Title

Prior CABG Patients Evaluated for Saphenous VeIn grAft DysfUnction and Progression of Coronary arTery Disease

Research Team

P

Paul Knaapen, Professor

R

Ruben de Winter, MD

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