Actively Recruiting

Age: 18Years +
FEMALE
NCT07263490

PRIOR Study (Pre-eclampsia Risk In Oocyte Recipients)

Led by Copenhagen University Hospital, Hvidovre · Updated on 2026-04-13

462

Participants Needed

6

Research Sites

188 weeks

Total Duration

On this page

Sponsors

C

Copenhagen University Hospital, Hvidovre

Lead Sponsor

F

Ferring Pharmaceuticals

Collaborating Sponsor

AI-Summary

What this Trial Is About

The aim of this prospective observational cohort study is to investigate the pathophysiological mechanisms behind and risk of pre-eclampsia in women pregnant after fertility treatment with oocyte donation. The participants are included in of of two cohorts. One includes women pregnant after oocyte donation whereas the other includes women pregnant after IVF treatment with autologous oocytes. Participants will be followed throughout pregnancy with blood samples, blood pressure, clinical controls and ultrasound examinations. Clinical outcomes will be registered post-partum.

CONDITIONS

Official Title

PRIOR Study (Pre-eclampsia Risk In Oocyte Recipients)

Who Can Participate

Age: 18Years +
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Age > 18 years
  • BMI < 35 kg/m2
  • Normal wet smear within the past three years
  • Both nulliparous and multiparous women
  • Includes both singleton and multiple pregnancies
Not Eligible

You will not qualify if you...

  • Age < 18 years
  • BMI > 35 kg/m2
  • HIV or hepatitis infection
  • Essential hypertension
  • Chronic kidney disease
  • Undiagnosed vaginal bleeding
  • Uterine malformations
  • Persisting ovarian cysts
  • Tumors in hypothalamus, pituitary, thyroid, or adrenal glands
  • Previous breast cancer
  • Known BRCA 1 or 2 gene mutation
  • Unregulated thyroid disease
  • Cardiovascular disease
  • Breastfeeding
  • Current or past chemotherapy or radiation therapy
  • Current or past malignant disease
  • Smoking
  • Alcohol or drug abuse

AI-Screening

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Trial Site Locations

Total: 6 locations

1

Copenhagen Fertility Center

Copenhagen, Denmark, 2400

Actively Recruiting

2

Trianglen Fertility Clinic

Hellerup, Denmark, 2900

Actively Recruiting

3

Fertility Clinic, Herlev / Gentofte Hospital

Herlev, Denmark, 2730

Actively Recruiting

4

Sellmer Klinik

København S, Denmark, 2300

Actively Recruiting

5

Fertility Clinic, Rigshospitalet

København Ø, Denmark, 2100

Actively Recruiting

6

Aleris Fertility

Søborg, Denmark, 2860

Actively Recruiting

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How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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