Actively Recruiting

Phase Not Applicable
Age: 18Years - 65Years
All Genders
NCT06729710

Prism Adaptation in Symptomatic Esophoria - Effect of Shorter Time Intervals and Surgical Outcomes Based on Prism Adaptation

Led by Rigshospitalet, Denmark · Updated on 2025-07-22

100

Participants Needed

1

Research Sites

241 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study is a prospective randomized study aiming to investigate the effect of prism adaptation before surgery for symptomatic esophoria on the number of reoperations, the occurrence of over- and under-correction after the first surgery, and symptom resolution. Additionally, we aim to define the optimal duration of prism adaptation.

CONDITIONS

Official Title

Prism Adaptation in Symptomatic Esophoria - Effect of Shorter Time Intervals and Surgical Outcomes Based on Prism Adaptation

Who Can Participate

Age: 18Years - 65Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients with symptomatic esophoria experiencing one or more of the following: double vision, eye strain (asthenopia), headaches related to esophoria, or worsening symptoms during fatigue, sleep deprivation, reading, illness, or alcohol consumption
Not Eligible

You will not qualify if you...

  • Age below 18 or above 65 years at time of inclusion
  • Accommodative esotropia or esophoria
  • Myopia over 10 diopters in the most myopic meridian
  • Botulinum toxin treatment in an eye muscle within 4 months before inclusion
  • Inability to undergo reliable orthoptic measurements or prism adaptation
  • Previous strabismus surgery
  • Pregnancy or breastfeeding within 12 months before inclusion
  • Myogenic disorders including Myasthenia Gravis
  • Restrictive strabismus including previous eye muscle trauma or Graves' orbitopathy
  • Eye muscle paresis
  • Maximum prism-adapted deviation angle greater than 40 prism diopters in any gaze direction for distance
  • Maximum prism-adapted deviation angle difference of 20 prism diopters or more between near and distance measurements

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Rigshospitalet

Copenhagen, Denmark, 2600

Actively Recruiting

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Research Team

M

Mikael Hofsli, M.D

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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