Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT05983185

Prism Adaptation Therapy (PAT) for Right Brain Stroke Rehabilitation

Led by VA Office of Research and Development · Updated on 2026-04-23

244

Participants Needed

4

Research Sites

256 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

After a right brain stroke, \>50% of Veterans experience problems with dressing, eating, self-care or steering their wheelchairs because their ability to move, orient, and respond toward the left side is limited: spatial neglect. Spatial neglect prevents them from functioning independently, and their needs in the hospital and at home are greatly increased. An effective treatment for spatial neglect is 10 days of visuomotor training while wearing optical prisms (PAT), however many clinicians \[fail to diagnose spatial neglect and use this approach. In this study, the investigators will develop a brain scanning test that could objectively identify the Veterans with spatial neglect after stroke who are the best candidates to receive PAT and recover their ability to function. When the research is complete, the investigators expect that brain scans done in the hospital can guide the team to refer Veterans to PAT rehabilitation: improving daily life function\] and quality of life.

CONDITIONS

Official Title

Prism Adaptation Therapy (PAT) for Right Brain Stroke Rehabilitation

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Has had a first right brain stroke and is older than 18 years
  • Stroke occurred 1 to 4 months before enrollment
  • Can sit up, see out of both eyes, and point to objects with vision better than 20/50
  • Can give informed consent to participate
Not Eligible

You will not qualify if you...

  • Diagnosed with other chronic disabling neurological disorders such as multiple sclerosis or Alzheimer Disease
  • Has had a clinical left brain stroke or prior strokes with more than two lacunes larger than 15 mm
  • Unable to sit up for testing and receiving prism adaptation therapy
  • Vision worse than 20/50 when viewing with both eyes

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 4 locations

1

VA Connecticut Healthcare System West Haven Campus, West Haven, CT

West Haven, Connecticut, United States, 06516-2770

Actively Recruiting

2

Atlanta VA Medical and Rehab Center, Decatur, GA

Decatur, Georgia, United States, 30033-4004

Actively Recruiting

3

VA Central Western Massachusetts Healthcare System, Leeds, MA

Leeds, Massachusetts, United States, 01053-9764

Actively Recruiting

4

Louis Stokes VA Medical Center, Cleveland, OH

Cleveland, Ohio, United States, 44106-1702

Actively Recruiting

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Research Team

A

Akila Sanjay, BA

CONTACT

A

Anna M Barrett, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

NON_RANDOMIZED

Model

SINGLE_GROUP

Primary Purpose

DIAGNOSTIC

Number of Arms

2

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