PRiSMA Study on Maternal and Newborn Health Monitoring Pregnancy Risks and Outcomes in Multiple Countries

What this Trial Is About

Access to quality antenatal and postnatal care is crucial to reducing pregnancy-related health problems and supporting positive birth experiences. Despite World Health Organization recommendations for eight antenatal visits, coverage and quality of care remain inconsistent, especially in vulnerable populations and resource-poor regions. This study aims to evaluate pregnancy risk factors and their links to adverse outcomes like stillbirth, neonatal mortality, and maternal morbidity in low- and middle-income countries to help improve maternal and newborn health. The study follows a large open cohort design to gather harmonized data on maternal and newborn health from multiple centers. It observes pregnant women from early pregnancy under 20 weeks gestation through delivery and postpartum periods, focusing on risk factors and outcomes without providing specific treatments. The research collects information on maternal mortality, severe maternal outcomes, anemia, stillbirth, neonatal mortality, preterm birth, low birth weight, and small-for-gestational-age infants. Participants will be monitored from pregnancy identification around 10-20 weeks gestation through delivery and up to one year postpartum. Assessments include maternal and infant health outcomes measured at various timepoints such as delivery, 42 days postpartum, and up to 12 months after birth. The study tracks important maternal and infant conditions, including infections, hypertension, diabetes, depression, and infant growth, aiming to better understand risks and inform future care strategies.

PRISMA Maternal and Newborn Health Study