Actively Recruiting
Pro-miniCHOP-like Regimen for Treatment-naive Elderly Patients
Led by The First Affiliated Hospital of Soochow University · Updated on 2023-04-20
35
Participants Needed
1
Research Sites
182 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The proposed study is a prospective, single-center and open-ended study in patients over the age of 70 with treatment-naive diffuse large B-cell lymphoma (DLBCL). This study intends to explore a new treatment pattern using Pro-miniCHOP-like regimen and simultaneously evaluate its safety and efficacy for future clinical practice.
CONDITIONS
Official Title
Pro-miniCHOP-like Regimen for Treatment-naive Elderly Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Histopathologically or cytologically confirmed newly diagnosed untreated diffuse large B-cell lymphoma (DLBCL)
- At least one measurable lesion of 15 mm or larger on imaging
- Age 70 years or older
- Life expectancy longer than 3 months
- Adequate organ function: liver enzymes, bilirubin, and creatinine less than 3 times the upper limit of normal; cardiac ejection fraction 50% or higher; oxygen saturation above 90% without oxygen support
- Signed informed consent obtained
You will not qualify if you...
- Severe liver or kidney dysfunction with enzyme or creatinine levels more than 3 times the upper limit of normal
- Symptomatic or significant heart disease (NYHA class 2 or higher)
- Uncontrolled active infection
- Central nervous system involvement of DLBCL
- History of blood vessel clots
- Presence of other active tumors
- Need for systemic corticosteroid treatment
- Psychological conditions preventing study participation or informed consent
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
the First Affiliated Hospital of Soochow University
Suzhou, Jiangsu, China, 215006
Actively Recruiting
Research Team
Z
Zhengming Jin
CONTACT
C
Changju Qu
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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