Actively Recruiting

Phase Not Applicable
Age: 0Days - 1Day
All Genders
Healthy Volunteers
NCT07054216

Probiotic for Infants

Led by Hvidovre University Hospital · Updated on 2025-08-28

378

Participants Needed

2

Research Sites

148 weeks

Total Duration

On this page

Sponsors

H

Hvidovre University Hospital

Lead Sponsor

U

University of Copenhagen

Collaborating Sponsor

AI-Summary

What this Trial Is About

The BABIES II study is a single-center, randomized, double-blinded, placebo-controlled study in newborns with an 8½ months intervention period from 14 days of age to 9 months of age followed by a 3-months short-term follow-up period until 1 year of age and a possible long-term follow-up until 18 years of age. The study will evaluate the effect of supplementation with a probiotic strain on different health outcomes.

CONDITIONS

Official Title

Probiotic for Infants

Who Can Participate

Age: 0Days - 1Day
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Pregnant person above 18 years of age in gestational week 36+0 to 38+0 at Visit 0
  • Singleton pregnancy
  • Ability to read and speak Danish
  • Plan to breastfeed
  • Provided voluntary written informed consent
  • Newborn born at full term (37+0 weeks or more)
  • Newborn birth weight at least 2500 g
  • Newborn APGAR score of 7 or higher within the first 5 minutes of life
Not Eligible

You will not qualify if you...

  • Pregnancy at 38 weeks + 0 or later at the time of recruitment
  • Pregnancy with significant fetal abnormality found at ultrasound at 19-20 weeks gestation
  • Alcohol or drug abuse
  • Plan to give birth at hospitals other than Copenhagen University Hospital Hvidovre
  • Pregnant person with any contraindications to breastfeeding
  • Newborn with congenital disorders affecting safety or study outcomes
  • Newborn admitted to Neonatal Intensive Care Unit for more than 24 hours
  • Participation in another clinical intervention study that could interfere
  • Use of probiotics other than the study product

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

Hvidovre Hospital

Hvidovre, Region Sjælland, Denmark, 2650

Actively Recruiting

2

Center for Klinisk Mikrobiom Forskning, Gastroenheden og Klinisk Mikrobiologisk Afdeling

Hvidovre, Denmark, 2650

Not Yet Recruiting

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Research Team

S

Sofie Ingdam Halkjær, MSc, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

QUADRUPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

OTHER

Number of Arms

2

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