Actively Recruiting
Probiotic Supplements in Osteoarthritis
Led by Beni-Suef University · Updated on 2026-01-30
146
Participants Needed
1
Research Sites
54 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The current study aims to evaluate the effectiveness of adding probiotics to the standard of care in improving OA patient-related outcomes such as pain, stiffness, and physical activity.
CONDITIONS
Official Title
Probiotic Supplements in Osteoarthritis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients aged over 18 years
- Both males and females
- Must meet the American College of Rheumatology (ACR) clinical criteria for knee osteoarthritis
- Must have symptomatic osteoarthritis in at least one knee (index knee)
You will not qualify if you...
- Diagnosis of rheumatoid arthritis or other active generalized inflammatory diseases affecting the gastrointestinal tract such as IBD or celiac disease
- Previous total knee replacement on the affected knee or currently on a waiting list for joint replacement
- History of surgeries like gastric bypass or other injuries interfering with osteoarthritis symptoms or physical activity
- Presence of malabsorption disorders or systemic organ failure (liver, kidney, or heart)
- Use of corticosteroids above 10 mg/day or intra-articular injections within the last 6 months
- Recent antibiotic treatment within 2 months before the study starts
- Pregnancy or breastfeeding
- Smoking more than 10 cigarettes per day
- Use of immunosuppressive treatment or having an impaired immune system
- Experiencing chronic or acute diarrhea
- Donated blood or plasma or received transfusions during the 3 months of the study
- Having uncontrolled diabetes
- Allergy to any ingredients of the study products
- Post-traumatic osteoarthritis, congenital hip deformities, or neurological conditions affecting pain perception
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Asmaa Abdelfattah Elsayed
Banī Suwayf, Egypt, 82511
Actively Recruiting
Research Team
A
Asmaa A Elsayed
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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