Evaluating a Procalcitonin-Based Approach to Improve Management of Adults with Uncomplicated Adhesion-Related Small Bowel Obstruction

What this Trial Is About

Adhesion-related small bowel obstruction ASBO is a common digestive emergency that can be treated either conservatively or with surgery. This condition carries a risk of death, especially if surgery is delayed. Researchers are evaluating a procalcitonin-based algorithm to improve decision-making between these treatment options, aiming to enhance patient management and outcomes. The study compares two approaches one uses clinical examination combined with procalcitonin blood tests to guide treatment decisions, while the other relies on clinical examination alone without procalcitonin testing. Patients in both groups initially receive conservative care including nasogastric tubes and intravenous fluids, with surgery considered after 48 hours if bowel function does not return. The algorithm arm uses specific procalcitonin thresholds to identify patients needing surgery sooner. Participants will be monitored for up to 90 days to see how many achieve a textbook outcome, which reflects quality care. Additional assessments include patient satisfaction questionnaires, complication scores, and length of hospital stay up to 12 months after surgery. The study involves clinical exams, blood tests, and follow-ups to evaluate the impact of the algorithm on treatment timing and patient recovery.

A Procalcitonin-based Algorithm in Adhesion-related Small Bowel Obstruction