Actively Recruiting

Age: 18Years +
MALE
NCT06835218

PROCARE - PROstate Cancer Real World Evidence Registry

Led by UroTrials Company (GmbH) · Updated on 2026-03-12

5000

Participants Needed

53

Research Sites

465 weeks

Total Duration

On this page

Sponsors

U

UroTrials Company (GmbH)

Lead Sponsor

N

Novartis Pharmaceuticals

Collaborating Sponsor

AI-Summary

What this Trial Is About

The aim of this registry study with long-term follow-up is to record the course of therapy and disease in patients with recurrent and metastatic prostate cancer. The following patient groups are planned: * Patients with a recurrence of PSA after surgical removal or radiation of the prostate due to prostate cancer; so-called PSA recurrence (relapse) or biochemical recurrence. * Patients with a PSA recurrence who have received treatment by hormone deprivation therapy (so-called androgen deprivation) and in whom the PSA value has nevertheless risen again without spreading to other organs or parts of the body, so-called non-metastatic castration-resistant prostate cancer. * Patients with proven spread to other organs or parts of the body (= metastases, e.g. in the bone) without hormone deprivation therapy having been initiated, so-called metastatic hormone-sensitive prostate cancer. * Patients with prostate cancer and spread to other organs or parts of the body (= metastases) in whom the tumor disease has progressed despite hormone withdrawal treatment (e.g. as evidenced by an increase in PSA), so-called metastatic castration-refractory prostate cancer. These four groups of patients are enrolled and observed independently of each other at different time periods.

CONDITIONS

Official Title

PROCARE - PROstate Cancer Real World Evidence Registry

Who Can Participate

Age: 18Years +
MALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Adult prostate cancer patients aged 18 years or older
  • Diagnosis at time of study inclusion of one of the following: biochemical recurrence after local curative treatment, non-metastatic castration-resistant prostate cancer, metastatic hormone-sensitive prostate cancer, or metastatic castration-resistant prostate cancer
  • Patients starting a new line of systemic therapy at study entry or within 4 weeks thereafter
  • For certain cohorts, disease must be proven by standard imaging to be unsuitable for or declined local salvage treatment
  • Ability and willingness to sign the informed consent form
Not Eligible

You will not qualify if you...

  • Patients considered ineligible for observation due to severe comorbidities or unavailability as determined by the treating physician

AI-Screening

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Trial Site Locations

Total: 53 locations

1

Universitätsklinikum Freiburg

Freiburg im Breisgau, Baden-Wurttemberg, Germany, 79106

Actively Recruiting

2

National Center for Tumor Dieseases (NCT) Heidelberg

Heidelberg, Baden-Wurttemberg, Germany, 69120

Actively Recruiting

3

University Hospital Mannheim

Mannheim, Baden-Wurttemberg, Germany, 68167

Actively Recruiting

4

Medical Office for Urology Nürtingen

Nürtingen, Baden-Wurttemberg, Germany, 72622

Actively Recruiting

5

Studienpraxis Urologie

Nürtingen, Baden-Wurttemberg, Germany, 72622

Actively Recruiting

6

University Hospital Tübingen

Tübingen, Baden-Wurttemberg, Germany, 72076

Actively Recruiting

7

University Hospital Ulm

Ulm, Baden-Wurttemberg, Germany, 89081

Actively Recruiting

8

University Hospital Augsburg

Augsburg, Bavaria, Germany, 86156

Actively Recruiting

9

University Hospital Augsburg

Augsburg, Bavaria, Germany, 86156

Actively Recruiting

10

Hospital Bayreuth GmbH

Bayreuth, Bavaria, Germany, 95445

Actively Recruiting

11

University Hospital Erlangen

Erlangen, Bavaria, Germany, 91054

Actively Recruiting

12

Hospital Kempten

Kempten (Allgäu), Bavaria, Germany, 87439

Actively Recruiting

13

Hospital Nürnberg North

Nuremberg, Bavaria, Germany, 90419

Actively Recruiting

14

Caritas-Hospital St. Josef

Regensburg, Bavaria, Germany, 93053

Actively Recruiting

15

University Hospital Würzburg

Würzburg, Bavaria, Germany, 97080

Actively Recruiting

16

"Vivantes Prostatazentrum" Hospital "am Urban"

Berlin, Brandenburg, Germany, 10967

Actively Recruiting

17

University Hospital Hamburg-Eppendorf

Hamburg, Free and Hanseatic City of Hamburg, Germany, 20246

Actively Recruiting

18

University Hospital Frankfurt/Main

Frankfurt am Main, Hesse, Germany, 60590

Actively Recruiting

19

Universitiy Hospital Gießen und Marburg GmbH, Site: Gießen

Giessen, Hesse, Germany, 35392

Actively Recruiting

20

Universital Hospital Gießen & Marburg GmbH, Site: Marburg

Marburg, Hesse, Germany, 35043

Actively Recruiting

21

Hospital Wetzlar

Wetzlar, Hesse, Germany, 35578

Actively Recruiting

22

Medical Office for Urology

Braunschweig, Lower Saxony, Germany, 38100

Actively Recruiting

23

Medical Office for Urology

Herzberg am Harz, Lower Saxony, Germany, 37412

Actively Recruiting

24

St. Bernward Hospital Hildesheim

Hildesheim, Lower Saxony, Germany, 31134

Actively Recruiting

25

St. Bernward Krankenhaus GmbH

Hildesheim, Lower Saxony, Germany, 31134

Actively Recruiting

26

Medical Office for Urology Altstadtquartier Magdeburg

Magdeburg, Lower Saxony, Germany, 39104

Actively Recruiting

27

MVZ Onco Medical GmbH Neustadt

Neustadt am Rübenberge, Lower Saxony, Germany, 31535

Actively Recruiting

28

Praxisgemeinschaft f. Onkologie & Urologie

Wilhelmshaven, Lower Saxony, Germany, 26389

Actively Recruiting

29

University Hospital Rostock

Rostock, Mecklenburg-Vorpommern, Germany, 18057

Actively Recruiting

30

University Hospital Aachen

Aachen, North Rhine-Westphalia, Germany, 52074

Actively Recruiting

31

Medical Office for Urology

Bayenthal, North Rhine-Westphalia, Germany, 50968

Actively Recruiting

32

Marien Hospital Bergisch Gladbach,

Bergisch Gladbach, North Rhine-Westphalia, Germany, 51465

Actively Recruiting

33

Johanniter GmbH, Johanniterkrankenhaus

Bonn, North Rhine-Westphalia, Germany, 53113

Actively Recruiting

34

Johanniter Hosptal Bonn

Bonn, North Rhine-Westphalia, Germany, 53113

Actively Recruiting

35

University Hospital Bonn

Bonn, North Rhine-Westphalia, Germany, 53127

Actively Recruiting

36

Medical Office for Urology "Urologicum"

Duisburg, North Rhine-Westphalia, Germany, 47169

Actively Recruiting

37

University Hospital Düsseldorf

Düsseldorf, North Rhine-Westphalia, Germany, 40225

Actively Recruiting

38

University Hospital Essen

Essen, North Rhine-Westphalia, Germany, 45147

Actively Recruiting

39

Marien Hospital Herne, University Hospital der Ruhr-Universität Bochum

Herne, North Rhine-Westphalia, Germany, 44625

Actively Recruiting

40

"Brüder" Hospital St. Joseph Paderborn

Paderborn, North Rhine-Westphalia, Germany, 33098

Actively Recruiting

41

University Hospital Wuppertal

Wuppertal, North Rhine-Westphalia, Germany, 42283

Actively Recruiting

42

Medical Office for Urology

Würselen, North Rhine-Westphalia, Germany, 52146

Actively Recruiting

43

Urban Hospital Karlsruhe

Karlsruhe, Rhineland-Palatinate, Germany, 76133

Actively Recruiting

44

Hospital "Barmherzigen Brüder "Trier

Trier, Rhineland-Palatinate, Germany, 54292

Actively Recruiting

45

Center for Urology Boxberg

Neunkirchen, Saarland, Germany, 66538

Actively Recruiting

46

University Hospital Leipzig

Leipzig, Saxony, Germany, 04103

Actively Recruiting

47

City Hospital Dessau

Dessau, Saxony-Anhalt, Germany, 06847

Actively Recruiting

48

Universitiy Hospital Halle

Halle, Saxony-Anhalt, Germany, 06120

Actively Recruiting

49

University Hospital Halle

Halle, Saxony-Anhalt, Germany, 06120

Actively Recruiting

50

Urologie Altstadtquartier Magdeburg

Magdeburg, Saxony-Anhalt, Germany, 39104

Actively Recruiting

51

University Hospital Magdeburg

Magdeburg, Saxony-Anhalt, Germany, 39120

Actively Recruiting

52

Univerity Hospital Schleswig-Holstein

Lübeck, Schleswig-Holstein, Germany, 23562

Actively Recruiting

53

University Hospital Jena

Jena, Thuringia, Germany, 07747

Actively Recruiting

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Research Team

A

Andrea Rößler, PhD

CONTACT

L

Lisa Marx-Blümel, PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

4

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