Actively Recruiting

Phase Not Applicable
Age: 18Years - 70Years
All Genders
NCT06753409

Processed Electroencephalography-guided General Anesthesia and Outcomes in Major Abdominal Surgery

Led by Assiut University · Updated on 2025-02-04

162

Participants Needed

1

Research Sites

99 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study aims to evaluate whether the reduction in the amount of intraoperative norepinephrine required to prevent hypotension, facilitated by processed electroencephalography (pEEG) -guided general anesthesia, will lead to a decrease in postoperative complications, particularly acute kidney injury (AKI).

CONDITIONS

Official Title

Processed Electroencephalography-guided General Anesthesia and Outcomes in Major Abdominal Surgery

Who Can Participate

Age: 18Years - 70Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients scheduled for major abdominal surgery lasting more than 2 hours under general anesthesia
  • American Society of Anesthesiologists Physical Status (ASA) score I-III
  • Age between 18 and 70 years
  • Both male and female patients
Not Eligible

You will not qualify if you...

  • Emergency surgeries
  • Uncontrolled hypertension (systolic blood pressure >150 mm Hg) despite medication
  • Recent acute cardiovascular events such as heart failure or acute coronary syndrome
  • Chronic kidney disease with glomerular filtration rate below 30 ml/min/1.73 m² or requiring renal replacement therapy
  • Severe liver failure indicated by elevated liver enzymes, bilirubin, or low prothrombin time
  • Preoperative sepsis or septic shock
  • Pregnancy
  • Patient refusal to participate in the study

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Assiut University Hospitals

Asyut, Egypt

Actively Recruiting

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Research Team

W

Walaa H Mohamed, Assistant Lecturer

CONTACT

M

Mostafa S Abbas, Professor

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

2

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