Actively Recruiting

Age: 50Years - 99Years
All Genders
Healthy Volunteers
NCT04724941

Prodromal Alpha-Synuclein Screening in Parkinson's Disease Study

Led by University Hospital Schleswig-Holstein · Updated on 2025-09-22

2000

Participants Needed

1

Research Sites

339 weeks

Total Duration

On this page

Sponsors

U

University Hospital Schleswig-Holstein

Lead Sponsor

U

UCB Biopharma SRL

Collaborating Sponsor

AI-Summary

What this Trial Is About

The PASS-PD study is set out to screen individuals from the general population with an increased risk for the development of Parkinson's Disease (PD) and to investigate this highly enriched cohort longitudinally for five year. A special focus is placed on implementation of ethical standards for early risk disclosure in PD.

CONDITIONS

Official Title

Prodromal Alpha-Synuclein Screening in Parkinson's Disease Study

Who Can Participate

Age: 50Years - 99Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Age between 50 and 99 years
Not Eligible

You will not qualify if you...

  • Presence of clinical Parkinson's Disease at the time of study inclusion
  • Other significant neurologic diseases affecting the central nervous system (e.g. Multiple sclerosis)
  • Other significant diseases such as orthopedic diseases affecting quantitative motor assessment
  • For participants in the lumbar puncture substudy: contraindications for lumbar puncture such as bleeding tendency or use of anticoagulants

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Department for Neurology, University of Kiel

Kiel, Germany, 24118

Actively Recruiting

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Research Team

E

Eva Schaeffer, Dr.

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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